Literature DB >> 9112132

The cytotoxic interaction of inorganic trace elements with EDTA and cisplatin in sensitive and resistant human ovarian cancer cells.

R H Maier1, S M Purser, D L Nicholson, W J Pories.   

Abstract

Cisplatin (CDDP)-sensitive and -resistant human ovarian cells were studied in vitro with the objective of enhancing CDDP cytotoxicity by the addition of a metal and the chelate ethylenediaminetetraacetic acid (EDTA), to the CDDP. Chelateable elements, such as bismuth, calcium, cadmium, copper, iron, magnesium, selenium, vanadium, and zinc, when added to CDDP and in the presence of EDTA increased the cytotoxicity of the CDDP as compared to CDDP treatment alone.

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Year:  1997        PMID： 9112132     DOI： 10.1007/s11626-997-0145-8

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol Anim        ISSN： 1071-2690            Impact factor:   2.416


  18 in total

Review 1.  Mechanisms to improve chemotherapy effectiveness.

Authors:  R C Young
Journal:  Cancer       Date:  1990-02-01       Impact factor: 6.860

2.  Zinc-enhanced cytotoxicity in cisplatin sensitive and resistant human ovarian cancer cells.

Authors:  D L Nicholson; R H Maier; W J Pories
Journal:  In Vitro Cell Dev Biol Anim       Date:  1993-08       Impact factor: 2.416

Review 3.  Cancer of the ovary.

Authors:  S A Cannistra
Journal:  N Engl J Med       Date:  1993-11-18       Impact factor: 91.245

4.  Enhanced therapeutic efficacy of cisplatin by combination with diethyldithiocarbamate and hyperthermia in a mouse model.

Authors:  M S Murthy; L N Rao; J D Khandekar; E F Scanlon
Journal:  Cancer Res       Date:  1987-02-01       Impact factor: 12.701

Review 5.  Drugs five years later. Cisplatin.

Authors:  P J Loehrer; L H Einhorn
Journal:  Ann Intern Med       Date:  1984-05       Impact factor: 25.391

Review 6.  New cisplatin analogues in development. A review.

Authors:  Raymond B Weiss; Michaele C Christian
Journal:  Drugs       Date:  1993-09       Impact factor: 9.546

Review 7.  Comparative aspects of osteosarcoma. Dog versus man.

Authors:  S J Withrow; B E Powers; R C Straw; R M Wilkins
Journal:  Clin Orthop Relat Res       Date:  1991-09       Impact factor: 4.176

8.  Modulation of both cisplatin nephrotoxicity and drug resistance in murine bladder tumor by controlling metallothionein synthesis.

Authors:  M Satoh; D M Kloth; S A Kadhim; J L Chin; A Naganuma; N Imura; M G Cherian
Journal:  Cancer Res       Date:  1993-04-15       Impact factor: 12.701

9.  Prevention of lethal and renal toxicity of cis-diamminedichloroplatinum(II) by induction of metallothionein synthesis without compromising its antitumor activity in mice.

Authors:  A Naganuma; M Satoh; N Imura
Journal:  Cancer Res       Date:  1987-02-15       Impact factor: 12.701

10.  Tissue-specific induction of metallothionein by bismuth as a promising protocol for chemotherapy with repeated administration of cis-diamminedichloroplatinum (II) against bladder tumor.

Authors:  Y Kondo; M Satoh; N Imura; M Akimoto
Journal:  Anticancer Res       Date:  1992 Nov-Dec       Impact factor: 2.480
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