Literature DB >> 9111096

Brodifacoum intoxication with marijuana smoking.

F G La Rosa1, S H Clarke, J B Lefkowitz.   

Abstract

We report the case of a 17-year-old boy with a significant history of drug and alcohol abuse, which included smoking marijuana mixed with brodifacoum. As a consequence, the patient developed a prolonged coagulopathy that persisted for more than 1 year. To our knowledge, this is the first case reported in the literature in which super-warfarin intoxication has been associated with marijuana smoking. This report should increase the awareness of pathologists and clinicians when examining a patient with a history of drug abuse who exhibits persistent vitamin K1-dependent coagulopathy.

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Year:  1997        PMID: 9111096

Source DB:  PubMed          Journal:  Arch Pathol Lab Med        ISSN: 0003-9985            Impact factor:   5.534


  6 in total

1.  Detection of Brodifacoum and other Rodenticides in Drug Mixtures using Thermal Desorption Direct Analysis in Real Time Mass Spectrometry (TD-DART-MS).

Authors:  Elizabeth L Robinson; Edward Sisco
Journal:  J Forensic Sci       Date:  2018-12-10       Impact factor: 1.832

Review 2.  Superwarfarin (Long-Acting Anticoagulant Rodenticides) Poisoning: from Pathophysiology to Laboratory-Guided Clinical Management.

Authors:  Yeow-Kuan Chong; Tony Wing-Lai Mak
Journal:  Clin Biochem Rev       Date:  2019-11

3.  Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells.

Authors:  Shivani Sachdev; Rochelle Boyd; Natasha L Grimsey; Marina Santiago; Mark Connor
Journal:  PeerJ       Date:  2019-09-25       Impact factor: 2.984

4.  A Case Report of Acquired Factor X Deficiency in a Patient With Multiple Myeloma.

Authors:  Taher Sabobeh; Emily K Brugioni; Amgad Masoud; Sheshadri Madhusudhana; Valerica Mateescu
Journal:  Cureus       Date:  2021-02-11

5.  Severe Vitamin K-dependent Coagulopathy from Rodenticide-contaminated Synthetic Cannabinoids: Emergency Department Presentations.

Authors:  Erik Wright; John W Hafner; Gregory Podolej; Douglas L Feinstein; Richard van Breemen; Israel Rubinstein; Steven Aks; Michael Wahl
Journal:  West J Emerg Med       Date:  2021-07-15

6.  Synthetic cannabinoid-associated coagulopathy secondary to long-acting anticoagulant rodenticides: Observational case series and management recommendations.

Authors:  Mona N Bahouth; Peggy Kraus; Kathryn Dane; Manuela Plazas Montana; William Tsao; Burton Tabaac; Jagar Jasem; Holly Schmidlin; Evan Einstein; Michael B Streiff; Satish Shanbhag
Journal:  Medicine (Baltimore)       Date:  2019-09       Impact factor: 1.817

  6 in total

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