Literature DB >> 9110580

Garlic: its anticarcinogenic and antitumorigenic properties.

J A Milner1.   

Abstract

Overall, several investigations indicate that garlic and its organic allyl sulfur components inhibit the cancer process. Furthermore, these studies reveal that the benefits of garlic are not limited to a specific species, a particular tissue, or a specific carcinogen. Finally, odor is not a prerequisite for the protection provided by garlic against the initiation of chemical carcinogenesis. Although the water-soluble compound S-allyl cysteine is effective in reducing the risk of chemically induced tumors in experimental animals, it has no effect on established tumors. However, oil-soluble compounds such as diallyl disulfide are effective in reducing the proliferation of neoplasms. Although the evidence supports the benefits of garlic, additional evidence is needed to determine the quantity needed by humans to minimize cancer risk.

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Year:  1996        PMID: 9110580     DOI: 10.1111/j.1753-4887.1996.tb03823.x

Source DB:  PubMed          Journal:  Nutr Rev        ISSN: 0029-6643            Impact factor:   7.110


  23 in total

1.  In vitro effectiveness of garlic (Allium sativum) extract on scolices of hydatid cyst.

Authors:  Mohammad Moazeni; Ali Nazer
Journal:  World J Surg       Date:  2010-11       Impact factor: 3.352

Review 2.  Garlic and onions: their cancer prevention properties.

Authors:  Holly L Nicastro; Sharon A Ross; John A Milner
Journal:  Cancer Prev Res (Phila)       Date:  2015-01-13

3.  Evaluation of the antileishmanial and cytotoxic effects of various extracts of garlic (Allium sativum) on Leishmania tropica.

Authors:  Hossein Mahmoudvand; Peyman Sepahvand; Sareh Jahanbakhsh; Mozhgan Azadpour
Journal:  J Parasit Dis       Date:  2014-08-31

Review 4.  Phytotherapy and Nutritional Supplements on Breast Cancer.

Authors:  C M Lopes; A Dourado; R Oliveira
Journal:  Biomed Res Int       Date:  2017-08-06       Impact factor: 3.411

5.  Differential miRNA expression in the mouse jejunum during garlic treatment of Eimeria papillata infections.

Authors:  Saleh Al-Quraishy; Denis Delic; Helmult Sies; Frank Wunderlich; Abdel Azeem S Abdel-Baki; Mohamed Abdel Monam Dkhil
Journal:  Parasitol Res       Date:  2011-02-08       Impact factor: 2.289

6.  Organosulfur compounds and possible mechanism of garlic in cancer.

Authors:  S H Omar; N A Al-Wabel
Journal:  Saudi Pharm J       Date:  2009-12-24       Impact factor: 4.330

7.  Diallyl disulfide enhances carbon ion beams-induced apoptotic cell death in cervical cancer cells through regulating Tap73 /ΔNp73.

Authors:  Cuixia Di; Chao Sun; Hongyan Li; Jing Si; Hong Zhang; Lu Han; Qiuyue Zhao; Yang Liu; Bin Liu; Guoying Miao; Lu Gan; Yuanyuan Liu
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

8.  In vitro assessment of oxidative stress and apoptotic mechanisms of garlic extract in the treatment of acute promyelocytic leukemia.

Authors:  Clement G Yedjou; Paul B Tchounwou
Journal:  J Cancer Sci Ther       Date:  2012-01-01

Review 9.  Chemical constituents and medicinal properties of Allium species.

Authors:  Salim M A Bastaki; Shreesh Ojha; Huba Kalasz; E Adeghate
Journal:  Mol Cell Biochem       Date:  2021-08-21       Impact factor: 3.396

10.  Dentinal tubule disinfection with 2% chlorhexidine, garlic extract, and calcium hydroxide against Enterococcus faecalis by using real-time polymerase chain reaction: In vitro study.

Authors:  Kandaswamy Eswar; Nagendrababu Venkateshbabu; Kalaiselvam Rajeswari; Deivanayagam Kandaswamy
Journal:  J Conserv Dent       Date:  2013-05
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