Literature DB >> 911052

Effects of lidocaine on the anesthetic requirements for nitrous oxide and halothane.

R S Himes, C A DiFazio, R G Burney.   

Abstract

The effects of various plasma concentrations of lidocaine on nitrous oxide anesthesia in man and halothane requirements in the dog were studied. The response to incision of the skin was observed in 20 patients who were anesthetized with nitrous oxide, 70% inspired, and oxygen, 30%, plus various plasma levels of lidocaine. In addition, changes in the MAC of halothane in dogs were observed at various levels of lidocaine. In both circumstances lidocaine concentrations of 3 to 6 microgram/ml decreased anesthetic requirements approximately 10 to 28%. At clinically common concentrations of lidocaine, significant decreases in anesthetic requirements should be anticipated.

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Year:  1977        PMID： 911052     DOI： 10.1097/00000542-197711000-00010

Source DB:  PubMed          Journal:  Anesthesiology        ISSN： 0003-3022            Impact factor:   7.892


  33 in total

Review 1.  ["Alternative" effects of local anesthetic agents].

Authors:  S Pecher; B W Böttiger; B Graf; M W Hollmann
Journal:  Anaesthesist       Date:  2004-04       Impact factor: 1.041

2.  Lidocaine infusion adjunct to total intravenous anesthesia reduces the total dose of propofol during intraoperative neurophysiological monitoring.

Authors:  Tod B Sloan; Paul Mongan; Clark Lyda; Antoun Koht
Journal:  J Clin Monit Comput       Date:  2013-08-31       Impact factor: 2.502

Review 3.  Safety considerations in the use of drug combinations during general anaesthesia.

Authors:  E S Ransom; R A Mueller
Journal:  Drug Saf       Date:  1997-02       Impact factor: 5.606

4.  TASK Channel Deletion Reduces Sensitivity to Local Anesthetic-induced Seizures.

Authors:  Guizhi Du; Xiangdong Chen; Marko S Todorovic; Shaofang Shu; Jaideep Kapur; Douglas A Bayliss
Journal:  Anesthesiology       Date:  2011-11       Impact factor: 7.892

Review 5.  Adverse effects and drug interactions associated with local and regional anaesthesia.

Authors:  M Naguib; M M Magboul; A H Samarkandi; M Attia
Journal:  Drug Saf       Date:  1998-04       Impact factor: 5.606

6.  The thermodynamics of general and local anesthesia.

Authors:  Kaare Graesbøll; Henrike Sasse-Middelhoff; Thomas Heimburg
Journal:  Biophys J       Date:  2014-05-20       Impact factor: 4.033

7.  The effect of intravenous lidocaine infusion on bispectral index during major abdominal surgery.

Authors:  Patrick Bazin; James Padley; Matthew Ho; Jennifer Stevens; Erez Ben-Menachem
Journal:  J Clin Monit Comput       Date:  2017-06-16       Impact factor: 2.502

8.  Lidocaine as a supplement to general anesthesia for extraction of third molars: serum levels.

Authors:  J Scaramella; G D Allen; W M Goebel; D Donaldson
Journal:  Anesth Prog       Date:  1979 Sep-Oct

9.  Lidocaine infusion as a rescue analgesic in the perioperative setting.

Authors:  C Clarke; I McConachie; R Banner
Journal:  Pain Res Manag       Date:  2008 Sep-Oct       Impact factor: 3.037

10.  Systemic lidocaine and human somatosensory-evoked potentials during sufentanil-isoflurane anaesthesia.

Authors:  A Schubert; M G Licina; G M Glaze; L Paranandi
Journal:  Can J Anaesth       Date:  1992-07       Impact factor: 5.063
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