Literature DB >> 9107355

Physiopathology of H3-receptors and pharmacology of betahistine.

P B Van Cauwenberge1, S E De Moor.   

Abstract

This article reviews published research on the physiology of histamine H3-receptors. The function of this inhibitory autoreceptor, its localisation and influence on histaminergic neurones as well as histamine-controlled processes are presented together with the role of H3-receptors in the vestibular system. In addition to a summary of the properties of the main H3-agonists and -antagonists, the pharmacology of betahistine and its place in the treatment of vertigo are discussed.

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Year:  1997        PMID： 9107355     DOI： 10.3109/00016489709124020

Source DB:  PubMed          Journal:  Acta Otolaryngol Suppl        ISSN： 0365-5237


  4 in total

1.  Benign paroxysmal positional vertigo: a study of two manoeuvres with and without betahistine.

Authors:  M Cavaliere; G Mottola; M Iemma
Journal:  Acta Otorhinolaryngol Ital       Date:  2005-04       Impact factor: 2.124

Review 2.  Diagnosis and treatment of cutaneous mastocytosis in children: practical recommendations.

Authors:  Mariana Castells; Dean D Metcalfe; Luis Escribano
Journal:  Am J Clin Dermatol       Date:  2011-08-01       Impact factor: 7.403

3.  Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomised rats.

Authors:  Filip Bergquist; Alasdair Ruthven; Mike Ludwig; Mayank B Dutia
Journal:  J Physiol       Date:  2006-10-12       Impact factor: 5.182

4.  Acute effects of betahistine hydrochloride on food intake and appetite in obese women: a randomized, placebo-controlled trial.

Authors:  Asem H Ali; Lisa B Yanoff; Elizabeth A Stern; Abena Akomeah; Amber Courville; Merel Kozlosky; Sheila M Brady; Karim A Calis; James C Reynolds; Melissa K Crocker; Nir Barak; Jack A Yanovski
Journal:  Am J Clin Nutr       Date:  2010-09-29       Impact factor: 7.045
  4 in total

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