Literature DB >> 9105679

The GABAA receptor alpha 6 subunit gene (Gabra6) is tightly linked to the alpha 1-gamma 2 subunit cluster on mouse chromosome 11.

K M Garrett1, D Haque, D Berry, I Niekrasz, J Gan, A Rotter, T W Seale.   

Abstract

We have established that the GABAA receptor alpha 6 (Gabra6) and alpha 1 (Gabra 1) subunit genes are tightly linked on mouse chromosome 11 by analysing the strain distribution patterns of RFLPs for the two genes and microsatellite markers flanking these genes in 26 BXD recombinant inbred strains. These results further demonstrate clustering of the GABAA receptor subunit genes on mouse chromosomes and the synteny for these clusters between the mouse and human genomes.

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Year:  1997        PMID： 9105679     DOI： 10.1016/s0169-328x(96)00290-2

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  8 in total

1.  GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus.

Authors:  S T Sinkkonen; M C Hanna; E F Kirkness; E R Korpi
Journal:  J Neurosci       Date:  2000-05-15       Impact factor: 6.167

2.  Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

Authors:  K J Buck; P Metten; J K Belknap; J C Crabbe
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

3.  Directing gene expression to cerebellar granule cells using gamma-aminobutyric acid type A receptor alpha6 subunit transgenes.

Authors:  S Bahn; A Jones; W Wisden
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-19       Impact factor: 11.205

4.  A sequence-ready BAC contig of the GABAA receptor gene cluster Gabrg1-Gabra2-Gabrb1 on mouse chromosome 5.

Authors:  A Lengeling; T Wiltshire; C Otmani; M Bucán
Journal:  Genome Res       Date:  1999-08       Impact factor: 9.043

5.  The cerebellar GABAAR α6-R100Q polymorphism alters ligand binding in outbred Sprague-Dawley rats in a similar manner as in selectively bred AT and ANT rats.

Authors:  Leena-Stiina Kontturi; Asko J Aalto; Martin Wallner; Mikko Uusi-Oukari
Journal:  Alcohol       Date:  2010-12-15       Impact factor: 2.405

6.  Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina.

Authors:  Maureen A McCall; Peter D Lukasiewicz; Ronald G Gregg; Neal S Peachey
Journal:  J Neurosci       Date:  2002-05-15       Impact factor: 6.167

7.  Kainate down-regulates a subset of GABAA receptor subunits expressed in cultured mouse cerebellar granule cells.

Authors:  Ilkka K Martikainen; Kadri Lauk; Tommi Möykkynen; Irma E Holopainen; Esa R Korpi; Mikko Uusi-Oukari
Journal:  Cerebellum       Date:  2004       Impact factor: 3.847

Review 8.  A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults.

Authors:  Jueun Kim; Aesoon Park
Journal:  Am J Addict       Date:  2018-07-10
  8 in total

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