Literature DB >> 9105550

Characterization of clofazimine metabolites in humans by HPLC-electrospray mass spectrometry.

D R Krishna1, R N Mamidi, U Hofmann, C M Prabhakar.   

Abstract

Clofazimine (CAS 2030-63-9) is an important drug used in the treatment of leprosy. Its important metabolites are investigated by thin layer chromatography (TLC), HPLC (diode array) and HPLC-electrospray mass spectrometry. The resulting analytical data, extraction, isolation and characterization methods are presented. Their applicability is described for human urine analysis.

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Year:  1997        PMID: 9105550

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  1 in total

1.  Characterization of Clofazimine Metabolism in Human Liver Microsomal Incubation In Vitro.

Authors:  Saurav Howlader; Min-Jung Kim; M Rasheduzzaman Jony; Nguyen Phuoc Long; Yong-Soon Cho; Dong-Hyun Kim; Jae-Gook Shin
Journal:  Antimicrob Agents Chemother       Date:  2022-10-03       Impact factor: 5.938

  1 in total

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