| Literature DB >> 9100992 |
Z Xiang1, K Ariyoshi, A Wilkins, F Dias, H Whittle, J Breuer.
Abstract
Data from an MRC case-control study in rural Guinea Bissau suggest older HIV-2 carriers (aged 55 to 80 years) appear, over a period of 2 years, to have a mortality similar to that of uninfected controls, whereas in HIV-2 carriers under the age of 55 there is a significantly higher mortality, compared with uninfected controls. Genotyping of viruses from both groups revealed only subtype a to be circulating. Thus, although putative nonpathogenic HIV-2 subtypes have been described in patients from West Africa, these do not appear to be contributing significantly to the nonpathogenic clinical phenotype in this population.Entities:
Keywords: Acquired Immunodeficiency Syndrome; Africa; Africa South Of The Sahara; Age Factors; Demographic Factors; Developing Countries; Differential Mortality; Diseases; Excess Mortality; Guinea-bissau; Hiv; Hiv Infections; Mortality; Population; Population Characteristics; Population Dynamics; Portuguese Speaking Africa; Research Report; Rural Population; Viral Diseases; Western Africa
Mesh：
Year: 1997 PMID： 9100992 DOI： 10.1089/aid.1997.13.501
Source DB: PubMed Journal: AIDS Res Hum Retroviruses ISSN： 0889-2229 Impact factor: 2.205