Literature DB >> 9100356

Syringaldazine. New attractive electron donor of prostaglandin H synthase.

Y A Kuznetsova1, V B Romakh.   

Abstract

The prostaglandin H synthase (PGHS) reaction has been studied with syringaldazine as the electron donor. Kinetic parameters of the reaction agreed with those for commonly used electron donors. The sensitivity of the PGHS activity detection in the presence of syringaldazine increases 10 times. A sensitive spectrophotometric assay for polyunsaturated fatty acid (PUFA) detection using syringaldazine as a new electron donor has been proposed.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 9100356     DOI： 10.1007/bf02785703

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN： 0273-2289            Impact factor:   2.926


  8 in total

1.  A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents.

Authors:  C Takeguchi; C J Sih
Journal:  Prostaglandins       Date:  1972-09

2.  Isolation and properties of intermediates in prostaglandin biosynthesis.

Authors:  D H Nugteren; E Hazelhof
Journal:  Biochim Biophys Acta       Date:  1973-12-20

3.  Prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. Inactivation and activation by heme and other metalloporphyrins.

Authors:  N Ogino; S Ohki; S Yamamoto; O Hayaishi
Journal:  J Biol Chem       Date:  1978-07-25       Impact factor: 5.157

4.  Prostaglandin hydroperoxidase, an integral part of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

Authors:  S Ohki; N Ogino; S Yamamoto; O Hayaishi
Journal:  J Biol Chem       Date:  1979-02-10       Impact factor: 5.157

5.  [Changes in the level of polyunsaturated fatty acids, substrates and inhibitors of thromboxane and prostacyclin synthesis, in the blood of patients with cardiovascular diseases].

Authors:  A T Mevkh; A K Ius'kovich; V S Duzhenko; E D Li; K M Lakin
Journal:  Kardiologiia       Date:  1990-09       Impact factor: 0.395

6.  Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis.

Authors:  M Hamberg; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

7.  Purification and characterisation of prostaglandin endoperoxide synthetase from sheep vesicular glands.

Authors:  F J Van der Ouderaa; M Buytenhek; D H Nugteren; D A Van Dorp
Journal:  Biochim Biophys Acta       Date:  1977-05-25

8.  Purification of prostaglandin H synthetase and a fluorometric assay for its activity.

Authors:  A T Mevkh; G F Sud'ina; N B Golub; S D Varfolomeev
Journal:  Anal Biochem       Date:  1985-10       Impact factor: 3.365
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.