| Literature DB >> 9099824 |
C S Cobbs1, A Fenoy, D S Bredt, L J Noble.
Abstract
Reduced nicotinamide adenine dinucleotide phosphate-diaphorase (NADPHd) histochemistry and nitric oxide synthase (NOS) immunocytochemistry were performed on sections of brain after moderate traumatic brain injury. There was a pronounced increase in NADPHd reactivity and an induction of the endothelial NOS (eNOS) isoform in microvessels surrounding the cortical contusion by 24 h post-injury. This altered microvascular state may contribute to barrier breakdown and hyperemia which characterize traumatic brain injury.Entities:
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Year: 1997 PMID: 9099824 DOI: 10.1016/s0006-8993(96)01429-1
Source DB: PubMed Journal: Brain Res ISSN: 0006-8993 Impact factor: 3.252