Literature DB >> 9099793

Control of immunoglobulin gene rearrangements in developing B cells.

F Papavasiliou1, M Jankovic, S Gong, M C Nussenzweig.   

Abstract

The antigen receptor on B lymphocytes is the product of a series of gene rearrangements which ends when a functional receptor gene is assembled. Recent work has shown that the receptor-associated molecules Ig alpha and Ig beta provide the signals that lead to inhibition of further recombination. Furthermore, Ig beta has been implicated in initiating the last step of the recombination reaction.

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Year:  1997        PMID： 9099793     DOI： 10.1016/s0952-7915(97)80141-0

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  5 in total

1.  Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.

Authors:  W M Hempel; P Stanhope-Baker; N Mathieu; F Huang; M S Schlissel; P Ferrier
Journal:  Genes Dev       Date:  1998-08-01       Impact factor: 11.361

2.  Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production.

Authors:  Johannes Lutz; Marinus R Heideman; Edith Roth; Paul van den Berk; Werner Müller; Chander Raman; Matthias Wabl; Heinz Jacobs; Hans-Martin Jäck
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-13       Impact factor: 11.205

3.  The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci.

Authors:  L Ardouin; J Ismaili; B Malissen; M Malissen
Journal:  J Exp Med       Date:  1998-01-05       Impact factor: 14.307

4.  The Ig heavy chain protein but not its message controls early B cell development.

Authors:  Muhammad Assad Aslam; Mir Farshid Alemdehy; Bingtao Hao; Peter H L Krijger; Colin E J Pritchard; Iris de Rink; Fitriari Izzatunnisa Muhaimin; Ika Nurzijah; Martijn van Baalen; Ron M Kerkhoven; Paul C M van den Berk; Jane A Skok; Heinz Jacobs
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-23       Impact factor: 11.205

5.  A role for the IgH intronic enhancer E mu in enforcing allelic exclusion.

Authors:  Fubin Li; Laurel A Eckhardt
Journal:  J Exp Med       Date:  2008-12-29       Impact factor: 14.307
  5 in total

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