Literature DB >> 9099792

Advances in gene targeting methods.

R Kühn1, F Schwenk.   

Abstract

Gene targeting in embryonic stem cells is commonly used for gene inactivation and the generation of mouse mutants. The combined use of methods for site-specific and homologous DNA recombination expands the potential of gene targeting in embryonic stem cells considerably and offers the opportunity of conditional gene targeting in mice.

Entities:  

Mesh：

Year:  1997        PMID： 9099792     DOI： 10.1016/s0952-7915(97)80133-1

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  8 in total

1.  Ablation of a specific cell population by the replacement of a uniquely expressed gene with a toxin gene.

Authors:  K Arase; K Saijo; H Watanabe; A Konno; H Arase; T Saito
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

Review 2.  Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination.

Authors:  Ravi P Misra; Stephen A Duncan
Journal:  Endocrine       Date:  2002-12       Impact factor: 3.633

Review 3.  Mechanisms of gene targeting in higher eukaryotes.

Authors:  Akinori Tokunaga; Hirofumi Anai; Katsuhiro Hanada
Journal:  Cell Mol Life Sci       Date:  2015-10-27       Impact factor: 9.261

Review 4.  Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy.

Authors:  Ethlinn V B van Gaal; Wim E Hennink; Daan J A Crommelin; Enrico Mastrobattista
Journal:  Pharm Res       Date:  2006-05-26       Impact factor: 4.200

5.  Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

Authors:  B E Clausen; C Burkhardt; W Reith; R Renkawitz; I Förster
Journal:  Transgenic Res       Date:  1999-08       Impact factor: 2.788

6.  Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene.

Authors:  J M Waldburger; T Suter; A Fontana; H Acha-Orbea; W Reith
Journal:  J Exp Med       Date:  2001-08-20       Impact factor: 14.307

7.  GRASP65 controls the cis Golgi integrity in vivo.

Authors:  Tineke Veenendaal; Tim Jarvela; Adam G Grieve; Johan H van Es; Adam D Linstedt; Catherine Rabouille
Journal:  Biol Open       Date:  2014-05-02       Impact factor: 2.422

8.  Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors.

Authors:  Richard J Fish; Egbert K O Kruithof
Journal:  BMC Mol Biol       Date:  2004-08-03       Impact factor: 2.946
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.