Literature DB >> 9098980

Refractive-index detection by interferometric backscatter in packed-capillary high-performance liquid chromatography.

C K Kenmore1, S R Erskine, D J Bornhop.   

Abstract

A simple, inexpensive, micro-volume refractive index detector has been applied to packed capillary high-performance liquid chromatography. Nanoliter detector volumes produced by a unique optical train, based on interferometric backscatter, allows for universal solute detection at the picogram level. System utility is demonstrated by reversed-phase separation of a test mixture containing ppm levels of NaCl, phenol, ethyl benzene and toluene.

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Year:  1997        PMID: 9098980     DOI: 10.1016/s0021-9673(96)00852-7

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  2 in total

1.  An Analysis of Semicircular Channel Backscattering Interferometry through Ray Tracing Simulations.

Authors:  Niall M C Mulkerns; William H Hoffmann; Ian D Lindsay; Henkjan Gersen
Journal:  Sensors (Basel)       Date:  2022-06-06       Impact factor: 3.847

2.  Critical assessment of relevant methods in the field of biosensors with direct optical detection based on fibers and waveguides using plasmonic, resonance, and interference effects.

Authors:  Günter Gauglitz
Journal:  Anal Bioanal Chem       Date:  2020-04-20       Impact factor: 4.142

  2 in total

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