PURPOSE: To understand the pathophysiology of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE). METHODS: Indocyanine green (ICG) angiography was used for three patients, four eyes with acute AMPPPE and four eyes with healed AMPPPE. RESULTS: The angiographic photographs demonstrated widespread choroidal hypofluorescence of the active and healed lesions. CONCLUSIONS: Although the pathogenesis and histopathology of AMPPPE are unknown, the literature suggests that AMPPPE may represent an inflammatory reaction, possibly a delayed-type hypersensitivity reaction. The ICG choroidal hypofluorescence in AMPPPE is probably due to partial choroidal vascular occlusion secondary to occlusive vasculitis.
PURPOSE: To understand the pathophysiology of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE). METHODS:Indocyanine green (ICG) angiography was used for three patients, four eyes with acute AMPPPE and four eyes with healed AMPPPE. RESULTS: The angiographic photographs demonstrated widespread choroidal hypofluorescence of the active and healed lesions. CONCLUSIONS: Although the pathogenesis and histopathology of AMPPPE are unknown, the literature suggests that AMPPPE may represent an inflammatory reaction, possibly a delayed-type hypersensitivity reaction. The ICG choroidal hypofluorescence in AMPPPE is probably due to partial choroidal vascular occlusion secondary to occlusive vasculitis.
Authors: Michael J Heiferman; Safa Rahmani; Lee M Jampol; Peter L Nesper; Dimitra Skondra; Leo A Kim; Amani A Fawzi Journal: Retina Date: 2017-11 Impact factor: 4.256
Authors: Meisha L Raven; Alexander L Ringeisen; Yoshihiro Yonekawa; Maxwell S Stem; Lisa J Faia; Justin L Gottlieb Journal: Int J Retina Vitreous Date: 2017-03-20