A J Flach1, R E Smith, F T Fraunfelder. 1. University of California, San Francisco Medical Center, Department of Ophthalmology, Corte Madera 94976, USA.
Abstract
BACKGROUND: Systemic acetazolamide treatment has been reported in association with Stevens-Johnson syndrome (SJS). This is the first report of this syndrome associated with methazolamide treatment. The association is reported in two Japanese-American women. METHOD AND RESULTS: Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed. CONCLUSIONS: Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.
BACKGROUND: Systemic acetazolamide treatment has been reported in association with Stevens-Johnson syndrome (SJS). This is the first report of this syndrome associated with methazolamide treatment. The association is reported in two Japanese-American women. METHOD AND RESULTS: Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed. CONCLUSIONS: Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.
Authors: F Yang; J Xuan; J Chen; H Zhong; H Luo; P Zhou; X Sun; L He; S Chen; Z Cao; X Luo; Q Xing Journal: Pharmacogenomics J Date: 2015-04-28 Impact factor: 3.550