Literature DB >> 9097808

Scleritis after glaucoma filtering surgery with mitomycin C.

S Fourman1.   

Abstract

BACKGROUND: Adjunctive intraoperative mitomycin C increases the success of glaucoma filtering surgery, but also the postoperative complications. This is the first report of scleritis after its use. PATIENTS: In five patients, scleritis developed 3 to 24 weeks after inferior trabeculectomy with mitomycin C. The onset was characterized by acute pain, redness of the eye, and decreased vision. Three patients had anterior scleritis and two had posterior scleritis. Infection or bleb leakage was not seen in any patient.
RESULTS: All patients responded to a course of topical steroids and oral ibuprofen or prednisone.
CONCLUSION: Anterior and posterior scleritis may complicate the use of topical mitomycin C during trabeculectomy, Prompt diagnosis and treatment reverses the inflammation, maintaining the success of the surgical procedure.

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Year:  1995        PMID: 9097808     DOI: 10.1016/s0161-6420(95)30829-9

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  6 in total

1.  Mitomycin C dissolved in a reversible thermosetting gel: target tissue concentrations in the rabbit eye.

Authors:  K Ichien; T Yamamoto; Y Kitazawa; A Oguri; H Ando; Y Kondo
Journal:  Br J Ophthalmol       Date:  1997-01       Impact factor: 4.638

2.  Secondary glaucoma due to chronic scleritis: trabeculectomy in scleromalacia: a case report.

Authors:  W H Dean; S A Turner; A I McNaught
Journal:  Eye (Lond)       Date:  2013-11-15       Impact factor: 3.775

3.  Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: 12 years' experience.

Authors:  Madhavi Kurli; Paul T Finger
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-06-07       Impact factor: 3.117

4.  Topical mitomycin C chemotherapy for conjunctival melanoma and PAM with atypia.

Authors:  P T Finger; G Czechonska; S Liarikos
Journal:  Br J Ophthalmol       Date:  1998-05       Impact factor: 4.638

Review 5.  Looking into the future: Gene and cell therapies for glaucoma.

Authors:  András M Komáromy; Kristin L Koehl; Shin Ae Park
Journal:  Vet Ophthalmol       Date:  2021-01-07       Impact factor: 1.644

Review 6.  A review of the efficacy of mitomycin C in glaucoma filtration surgery.

Authors:  Ahmed Al Habash; Leyla Ali Aljasim; Ohoud Owaidhah; Deepak P Edward
Journal:  Clin Ophthalmol       Date:  2015-10-20
  6 in total

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