Literature DB >> 9095369

Preparation of succinimidyl and pentafluorophenyl active esters of 5- and 6-carboxyfluorescein.

M Adamczyk1, J R Fishpaugh, K J Heuser.   

Abstract

A mixture of 5- and 6-carboxyfluorescein was activated with 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride in the presence of either N-hydroxysuccinimide or pentafluorophenol to give the corresponding succinimidyl and pentafluorophenyl esters. The regioisomeric mixtures were separated to give the 5- and 6-succinimidyl and pentafluorophenyl active esters in > 98% purity.

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Year:  1997        PMID： 9095369     DOI： 10.1021/bc9600877

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  3 in total

1.  Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5.

Authors:  Andrew M Riley; Sabine Windhorst; Hong-Yin Lin; Barry V L Potter
Journal:  Chembiochem       Date:  2013-12-06       Impact factor: 3.164

2.  Separating the isomers--efficient synthesis of the N-hydroxysuccinimide esters of 5 and 6-carboxyfluorescein diacetate and 5 and 6-carboxyrhodamine B.

Authors:  Aurélie Brunet; Tashfeen Aslam; Mark Bradley
Journal:  Bioorg Med Chem Lett       Date:  2014-05-04       Impact factor: 2.823

3.  Hybrid Multimodal Imaging Synthons for Chemoselective and Efficient Biomolecule Modification with Chelator and Near-Infrared Fluorescent Cyanine Dye.

Authors:  Ralph Hübner; Valeska von Kiedrowski; Vanessa Benkert; Björn Wängler; Ralf Schirrmacher; Roland Krämer; Carmen Wängler
Journal:  Pharmaceuticals (Basel)       Date:  2020-09-16
  3 in total

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