| Literature DB >> 9094689 |
Y P Li1.
Abstract
Nucleolar shuttle protein B23 was found to bind to human immunodeficiency virus protein Tat, and this binding required the nucleolar localization motif of Tat. A fusion protein containing the B23 binding domain and beta-galactosidase caused mislocalization of Tat to the cytoplasm and inhibited the transactivation activity of Tat. These data suggest that B23 is a human factor necessary for the nucleolar localization of Tat.Entities:
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Year: 1997 PMID: 9094689 PMCID: PMC191564
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103