Literature DB >> 9094689

Protein B23 is an important human factor for the nucleolar localization of the human immunodeficiency virus protein Tat.

Y P Li1.   

Abstract

Nucleolar shuttle protein B23 was found to bind to human immunodeficiency virus protein Tat, and this binding required the nucleolar localization motif of Tat. A fusion protein containing the B23 binding domain and beta-galactosidase caused mislocalization of Tat to the cytoplasm and inhibited the transactivation activity of Tat. These data suggest that B23 is a human factor necessary for the nucleolar localization of Tat.

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Year:  1997        PMID: 9094689      PMCID: PMC191564     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  22 in total

1.  Posttranscriptional regulation by the human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex proteins through a heterologous RNA binding site.

Authors:  D McDonald; T J Hope; T G Parslow
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

2.  Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function.

Authors:  A W Cochrane; A Perkins; C A Rosen
Journal:  J Virol       Date:  1990-02       Impact factor: 5.103

3.  Nucleolar targeting signal of human T-cell leukemia virus type I rex-encoded protein is essential for cytoplasmic accumulation of unspliced viral mRNA.

Authors:  T Nosaka; H Siomi; Y Adachi; M Ishibashi; S Kubota; M Maki; M Hatanaka
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

4.  Tat protein from human immunodeficiency virus forms a metal-linked dimer.

Authors:  A D Frankel; D S Bredt; C O Pabo
Journal:  Science       Date:  1988-04-01       Impact factor: 47.728

5.  Major nucleolar proteins shuttle between nucleus and cytoplasm.

Authors:  R A Borer; C F Lehner; H M Eppenberger; E A Nigg
Journal:  Cell       Date:  1989-02-10       Impact factor: 41.582

6.  Nucleolar targeting signal of Rex protein of human T-cell leukemia virus type I specifically binds to nucleolar shuttle protein B-23.

Authors:  Y Adachi; T D Copeland; M Hatanaka; S Oroszlan
Journal:  J Biol Chem       Date:  1993-07-05       Impact factor: 5.157

7.  Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element.

Authors:  C Fankhauser; E Izaurralde; Y Adachi; P Wingfield; U K Laemmli
Journal:  Mol Cell Biol       Date:  1991-05       Impact factor: 4.272

8.  Functional substitution of the basic domain of the HIV-1 trans-activator, Tat, with the basic domain of the functionally heterologous Rev.

Authors:  T Subramanian; M Kuppuswamy; L Venkatesh; A Srinivasan; G Chinnadurai
Journal:  Virology       Date:  1990-05       Impact factor: 3.616

9.  Mutational analysis of functional domains in the HIV-1 Rev trans-regulatory protein.

Authors:  J Berger; C Aepinus; M Dobrovnik; B Fleckenstein; J Hauber; E Böhnlein
Journal:  Virology       Date:  1991-08       Impact factor: 3.616

10.  Interactions of minute virus of mice and adenovirus with host nucleoli.

Authors:  T H Walton; P T Moen; E Fox; J W Bodnar
Journal:  J Virol       Date:  1989-09       Impact factor: 5.103

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  41 in total

1.  A nucleolar TAR decoy inhibitor of HIV-1 replication.

Authors:  Alessandro Michienzi; Shirley Li; John A Zaia; John J Rossi
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-10       Impact factor: 11.205

Review 2.  Functional roles of HIV-1 Tat protein in the nucleus.

Authors:  Yana R Musinova; Eugene V Sheval; Carla Dib; Diego Germini; Yegor S Vassetzky
Journal:  Cell Mol Life Sci       Date:  2015-10-27       Impact factor: 9.261

Review 3.  Nucleophosmin and human cancer.

Authors:  Mi Jung Lim; Xin Wei Wang
Journal:  Cancer Detect Prev       Date:  2006-11-17

4.  Direct interaction of the human I-mfa domain-containing protein, HIC, with HIV-1 Tat results in cytoplasmic sequestration and control of Tat activity.

Authors:  Virginie W Gautier; Noreen Sheehy; Margaret Duffy; Kenichi Hashimoto; William W Hall
Journal:  Proc Natl Acad Sci U S A       Date:  2005-10-31       Impact factor: 11.205

5.  Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.

Authors:  S N Brady; L B Maggi; C L Winkeler; E A Toso; A S Gwinn; C L Pelletier; J D Weber
Journal:  Oncogene       Date:  2009-06-29       Impact factor: 9.867

Review 6.  Grabbing the genome by the NADs.

Authors:  Timothy D Matheson; Paul D Kaufman
Journal:  Chromosoma       Date:  2015-07-15       Impact factor: 4.316

7.  NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin Remodeling.

Authors:  Mikael S Lindström
Journal:  Biochem Res Int       Date:  2010-10-05

8.  In vitro nuclear interactome of the HIV-1 Tat protein.

Authors:  Virginie W Gautier; Lili Gu; Niaobh O'Donoghue; Stephen Pennington; Noreen Sheehy; William W Hall
Journal:  Retrovirology       Date:  2009-05-19       Impact factor: 4.602

9.  Potent inhibition of HIV-1 replication by a Tat mutant.

Authors:  Luke W Meredith; Haran Sivakumaran; Lee Major; Andreas Suhrbier; David Harrich
Journal:  PLoS One       Date:  2009-11-10       Impact factor: 3.240

10.  Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size.

Authors:  Christine Müller; Anna Bremer; Sandra Schreiber; Sabrina Eichwald; Cornelis F Calkhoven
Journal:  EMBO J       Date:  2010-01-14       Impact factor: 11.598

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