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Literature DB >> 9090870

New antihepatotoxic cerebroside from Lycium chinense fruits.

S Y Kim¹, Y H Choi, H Huh, J Kim, Y C Kim, H S Lee.

Abstract

Two cerebrosides isolated from Lycium chinense fruits have been characterized as 1-O-beta-D-glucopyranosyl-(2S, 3R,4E,8Z)-2-N-palmitoyloctadecasphinga-4,8-dienine+ ++ (1) and 1-O-beta-D-glucopyranosyl -(2S,3R,4E,8Z)-2-N-(2'-hydroxypalmitoyl)octadecasph inga-4,8-dienine (2). While 2 is already known, the structure of 1 was determined by spectral and chemical studies. Incubation of CCl4-intoxicated hepatocytes with 1 and 2, respectively, significantly reduced the levels of glutamic pyruvic transaminase (GPT) and sorbitol dehydrogenase (SDH) released by injured cells.

Entities: Chemical Species

Mesh：

Substances：

Year: 1997 PMID： 9090870 DOI： 10.1021/np960670b

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

13 in total

1. Two novel glucosylceramides from gonads and body walls of the Patagonian starfish Allostichaster inaequalis.

Authors: María E Díaz de Vivar; Alicia M Seldes; Marta S Maier
Journal: Lipids Date: 2002-06 Impact factor: 1.880

2. Pecipamide, a new sphingosine derivative from the cultures of Polyporus picipes (Basidiomycetes).

Authors: Yong Li; Ya-Tuan Ma; Yi Kuang; Jin-Ming Gao; Jian-Chun Qin
Journal: Lipids Date: 2010-04-27 Impact factor: 1.880

3. New glycosphingolipid containing an unusual sphingoid base from the basidiomycete Polyporus ellisii.

Authors: J M Gao; L Hu; Z J Dong; J K Liu
Journal: Lipids Date: 2001-05 Impact factor: 1.880

4. Discrimination of Lycium chinense and Lycium barbarum by taste pattern and betaine analysis.

Authors: Hye Won Lee; Young Hwa Kim; Yun Hee Kim; Gwan Ho Lee; Mi Young Lee
Journal: Int J Clin Exp Med Date: 2014-08-15

5. An isomeric mixture of novel cerebrosides isolated from Impatiens pritzellii reduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells.

Authors: Xuefeng Zhou; Lan Tang; Yonghong Liu
Journal: Lipids Date: 2009-07-17 Impact factor: 1.880

New antihepatotoxic cerebroside from Lycium chinense fruits.

1. Two novel glucosylceramides from gonads and body walls of the Patagonian starfish Allostichaster inaequalis.

2. Pecipamide, a new sphingosine derivative from the cultures of Polyporus picipes (Basidiomycetes).

3. New glycosphingolipid containing an unusual sphingoid base from the basidiomycete Polyporus ellisii.

4. Discrimination of Lycium chinense and Lycium barbarum by taste pattern and betaine analysis.

5. An isomeric mixture of novel cerebrosides isolated from Impatiens pritzellii reduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells.

6. A glucosylceramide with a novel ceramide and three novel ceramides from the basidiomycete Cortinarius umidicola.

7. Treatment of d-galactose induced mouse aging with Lycium barbarum polysaccharides and its mechanism study.

8. Study on antibacterial effect of medlar and hawthorn compound extract in vitro.

9. Antidepressant-like effects of lycii radicis cortex and betaine in the forced swimming test in rats.

10. Dietary sea cucumber cerebroside alleviates orotic acid-induced excess hepatic adipopexis in rats.