Literature DB >> 9090824

Euglena gracilis as a supplementary test organism for detecting biologically active compounds.

M Macor1, J Beno, J Grones, P Siekel, J Novotný.   

Abstract

The mutagenic activity of more than 120 antimicrobial agents and protective components was investigated. Only Kathon showed a consistent increase in revertant counts in the Ames test on Salmonella typhimurium. The hereditary bleaching test on Euglena gracilis used for detecting extranuclear mutations, showed positive results for Kathon, triethanolamine and diamine silver tetraborate.

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Year:  1996        PMID： 9090824     DOI： 10.1007/bf02816340

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  10 in total

1.  EFFECT OF NITROFURANS ON THE CHLOROPLAST SYSTEM OF EUGLENA GRACILIS.

Authors:  D R MCCALLA
Journal:  J Protozool       Date:  1965-02

2.  Streptomycin-induced chlorophyll-less races of Euglena.

Authors:  L PROVASOLI; S H HUTNER; A SCHATZ
Journal:  Proc Soc Exp Biol Med       Date:  1948-11

Review 3.  Interaction of drugs with extranuclear genetic elements and its consequences.

Authors:  L Ebringer
Journal:  Teratog Carcinog Mutagen       Date:  1990

4.  Effect of elevated temperature on genotoxicity of chemotherapeuticals toward Euglena gracilis.

Authors:  M Macor; L Ebringer
Journal:  Folia Microbiol (Praha)       Date:  1988       Impact factor: 2.099

5.  Effect of heat shock on the mutagenicity of mutagens and carcinogens in Euglena gracilis.

Authors:  O Chreno; J Krajcovic; L Ebringer; J Polónyi
Journal:  Teratog Carcinog Mutagen       Date:  1988

6.  Mutagenic activity of Kathon, an industrial biocide and cosmetics preservative containing 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one.

Authors:  C Wright; E Gingold; S Venitt; C Crofton-Sleigh
Journal:  Mutat Res       Date:  1983-01       Impact factor: 2.433

7.  Revised methods for the Salmonella mutagenicity test.

Authors:  D M Maron; B N Ames
Journal:  Mutat Res       Date:  1983-05       Impact factor: 2.433

8.  Mutation of the Euglena chloroplast system: the mechanism of bleaching by nitrosoguanidine and related compounds.

Authors:  D R McCalla
Journal:  J Protozool       Date:  1967-08

Review 9.  A review of the genotoxicity of food, drug and cosmetic colours and other azo, triphenylmethane and xanthene dyes.

Authors:  R D Combes; R B Haveland-Smith
Journal:  Mutat Res       Date:  1982-03       Impact factor: 2.433

10.  Hyperthermia and other factors increasing sensitivity of Euglena to mutagens and carcinogens.

Authors:  M Macor; L Ebringer; P Siekel
Journal:  Teratog Carcinog Mutagen       Date:  1985
  10 in total

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