Literature DB >> 9090312

Preventing post-traumatic epilepsy after brain injury: weighing the costs and benefits of anticonvulsant prophylaxis.

T D Hernandez1.   

Abstract

If the primary goal in the treatment of traumatic brain injury is the minimization of post-injury morbidity, treatment strategies that effectively prevent the development of post-traumatic epilepsy and have a beneficial (or at least neutral) impact on functional recovery are necessary. Here, Theresa Hernandez discusses the degree to which the current post-injury practice of anticonvulsant prophylaxis satisfies each of these criteria.

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Year:  1997        PMID: 9090312

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


  4 in total

Review 1.  Pharmacological prophylaxis of post-traumatic epilepsy.

Authors:  A Iudice; L Murri
Journal:  Drugs       Date:  2000-05       Impact factor: 9.546

2.  The novel antiepileptic agent RWJ-333369-A, but not its analog RWJ-333369, reduces regional cerebral edema without affecting neurobehavioral outcome or cell death following experimental traumatic brain injury.

Authors:  Carrie A Keck; Hilaire J Thompson; Asla Pitkänen; David G LeBold; Diego M Morales; Jamie B Plevy; Rishi Puri; Boyu Zhao; Marc Dichter; Tracy K McIntosh
Journal:  Restor Neurol Neurosci       Date:  2007       Impact factor: 2.406

3.  Modeling of Age-Dependent Epileptogenesis by Differential Homeostatic Synaptic Scaling.

Authors:  Oscar C González; Giri P Krishnan; Sylvain Chauvette; Igor Timofeev; Terrence Sejnowski; Maxim Bazhenov
Journal:  J Neurosci       Date:  2015-09-30       Impact factor: 6.167

Review 4.  5-HT3 Receptors: A Potential Therapeutic Target for Epilepsy.

Authors:  Hongyan Zhao; Yang Lin; Shurui Chen; Xin Li; Hongliang Huo
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

  4 in total

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