Immunotherapy for house dust allergy.

The results of treatment in 201 patients with rhinoconjuctivitis due to house dust mite-induced allergy are reported. Bronchial asthma was associated with this condition in 45 of the patients (22.3%). Of the 201, 143 patients in whom symptomatic therapy was not sufficiently efficacious, received immunotherapy (hyposensitization). In most of the 143 patients, hyposensitization with Alutard allergen extract resulted in marked improvement, rendering 107 patients (75%) free of symptoms and signs. The remaining 36 responded as follows: the patient's condition improved considerably in 14 (10%), in seven (5%) it improved, in 10 (7%) it remained unchanged, and in five (3%) it worsened. During the hyposensitization, generalized urticaria was seen in three patients, oedema of the upper part of the body in one, and generalized pruritus and dysponea in one.