Community based studies on childhood mortality in a malaria holoendemic area on the Tanzanian coast.

Demographic surveillance of children under 5 years of age was undertaken over a 2 year period in a rural area of coastal Tanzania where holoendemic malaria conditions exist. The mean annual entomological innoculation rate (EIR) during the period under study was 234 infective bites per person. There were 192 deaths in children and 1130 live births during the 2 years. Of these, 148 were infant deaths giving an infant mortality rate of 131/1000 live births (95% CI 101, 154). There were 44 deaths in children 1-4 years of age and the overall child mortality rate was 10/1000 (95% CI 6.1, 14.3). Using verbal autopsy questionnaires, 56% of the deaths under 4 years were tentatively attributed to malaria.