Literature DB >> 9088112

Telomere shortening in peripheral blood cells was related with aging but not with white blood cell count.

H Satoh1, K Hiyama, M Takeda, Y Awaya, K Watanabe, Y Ihara, H Maeda, S Ishioka, M Yamakido.   

Abstract

Telomeres in somatic cells are progressively shortened with aging. We investigated the relationship between the telomere length and other factors which may affect the frequency of cell divisions, in peripheral blood cells. Shortening of telomeric repeats was correlated with aging (p < 0.0001), but not with white blood cell count, neutrophil count, and smoking habit. Not only the number of cell divisions, but also some other factors, such as upregulation level of telomerase activity concomitant with the cell division in hematopoietic progenitor cells, might affect the length of telomeric repeats in blood cells.

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Year:  1996        PMID: 9088112     DOI: 10.1007/BF01876332

Source DB:  PubMed          Journal:  Jpn J Hum Genet        ISSN: 0916-8478


  8 in total

Review 1.  Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease.

Authors:  Siobhán Q Gregg; Andria Rasile Robinson; Laura J Niedernhofer
Journal:  DNA Repair (Amst)       Date:  2011-05-25

2.  Accelerated telomere shortening in response to life stress.

Authors:  Elissa S Epel; Elizabeth H Blackburn; Jue Lin; Firdaus S Dhabhar; Nancy E Adler; Jason D Morrow; Richard M Cawthon
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-01       Impact factor: 11.205

3.  Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: a population study.

Authors:  Karen A Mather; Anthony F Jorm; Kaarin J Anstey; Peter J Milburn; Simon Easteal; Helen Christensen
Journal:  BMC Geriatr       Date:  2010-09-16       Impact factor: 3.921

4.  Telomere Shortening, Regenerative Capacity, and Cardiovascular Outcomes.

Authors:  Muhammad Hammadah; Ibhar Al Mheid; Kobina Wilmot; Ronnie Ramadan; Naser Abdelhadi; Ayman Alkhoder; Malik Obideen; Pratik M Pimple; Oleksiy Levantsevych; Heval M Kelli; Amit Shah; Yan V Sun; Brad Pearce; Michael Kutner; Qi Long; Laura Ward; Yi-An Ko; Kareem Hosny Mohammed; Jue Lin; Jinying Zhao; J Douglas Bremner; Jinhee Kim; Edmund K Waller; Paolo Raggi; David Sheps; Arshed A Quyyumi; Viola Vaccarino
Journal:  Circ Res       Date:  2016-12-12       Impact factor: 17.367

Review 5.  Circulating endothelial progenitor cells: a new approach to anti-aging medicine?

Authors:  Nina A Mikirova; James A Jackson; Ron Hunninghake; Julian Kenyon; Kyle W H Chan; Cathy A Swindlehurst; Boris Minev; Amit N Patel; Michael P Murphy; Leonard Smith; Doru T Alexandrescu; Thomas E Ichim; Neil H Riordan
Journal:  J Transl Med       Date:  2009-12-15       Impact factor: 5.531

6.  Telomere Length Differently Associated to Obesity and Hyperandrogenism in Women With Polycystic Ovary Syndrome.

Authors:  Mariela Edith Velazquez; Andrea L Millan; Mailén Rojo; Giselle Adriana Abruzzese; Silvina Ema Cocucci; Andrea Elena Iglesias Molli; Gustavo Daniel Frechtel; Alicia Beatriz Motta; Gloria Edith Cerrone
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-14       Impact factor: 5.555

7.  Telomere Length Is Not Related to Established Cardiovascular Risk Factors but Does Correlate with Red and White Blood Cell Counts in a German Blood Donor Population.

Authors:  Bruno Neuner; Anna Lenfers; Reinhard Kelsch; Kathrin Jäger; Nina Brüggmann; Pim van der Harst; Michael Walter
Journal:  PLoS One       Date:  2015-10-07       Impact factor: 3.240

8.  Metabolically healthy obese women have longer telomere length than obese women with metabolic syndrome.

Authors:  Andrea E Iglesias Molli; Julieta Panero; Patricia C Dos Santos; Claudio D González; Jorge Vilariño; Marta Sereday; Gloria E Cerrone; Irma Slavutsky; Gustavo D Frechtel
Journal:  PLoS One       Date:  2017-04-06       Impact factor: 3.240

  8 in total

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