Literature DB >> 9087507

Early effects of ganciclovir therapy on the quantity of cytomegalovirus DNA in leukocytes of immunocompromised patients.

G Boivin1, M R Quirk, B A Kringstad, M Germain, M C Jordan.   

Abstract

The cytomegalovirus (CMV) DNA load in leukocytes was measured in 26 immunocompromised patients with CMV disease before and after 10 days of intravenous ganciclovir therapy. Before therapy, the circulating DNA burden of bone marrow transplant recipients was significantly lower than that of other transplant or AIDS patients. Ganciclovir induction therapy significantly decreased the viral DNA load in the leukocyte populations of most patients.

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Year:  1997        PMID： 9087507      PMCID： PMC163812     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

Review 1.  Impact of cytomegalovirus infection on organ transplant recipients.

Authors:  R H Rubin
Journal:  Rev Infect Dis       Date:  1990 Sep-Oct

2.  Comparison of culture and serology for the diagnosis of cytomegalovirus infection in kidney and liver transplant recipients.

Authors:  L Marsano; R P Perrillo; M W Flye; D W Hanto; E D Spitzer; J R Thomas; P R Murray; D W Windus; E M Brunt; G A Storch
Journal:  J Infect Dis       Date:  1990-03       Impact factor: 5.226

3.  Cytomegalovirus excretion as a predictor of cytomegalovirus disease after marrow transplantation: importance of cytomegalovirus viremia.

Authors:  J D Meyers; P Ljungman; L D Fisher
Journal:  J Infect Dis       Date:  1990-08       Impact factor: 5.226

4.  Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.

Authors:  G Gilliland; S Perrin; K Blanchard; H F Bunn
Journal:  Proc Natl Acad Sci U S A       Date:  1990-04       Impact factor: 11.205

5.  Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS.

Authors:  H H Balfour; C V Fletcher; A Erice; W K Henry; E P Acosta; S A Smith; M A Holm; G Boivin; D H Shepp; C S Crumpacker; C A Eaton; S S Martin-Munley
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

Review 6.  Nonbacterial pneumonia after allogeneic marrow transplantation: a review of ten years' experience.

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Journal:  Rev Infect Dis       Date:  1982 Nov-Dec

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Authors:  R L Saltzman; M R Quirk; M C Jordan
Journal:  J Clin Invest       Date:  1992-11       Impact factor: 14.808

8.  Monitoring of human cytomegalovirus infections and ganciclovir treatment in heart transplant recipients by determination of viremia, antigenemia, and DNAemia.

Authors:  G Gerna; D Zipeto; M Parea; M G Revello; E Silini; E Percivalle; M Zavattoni; P Grossi; G Milanesi
Journal:  J Infect Dis       Date:  1991-09       Impact factor: 5.226

9.  Predictive value of cytomegalovirus viraemia for the occurrence of CMV organ involvement in AIDS.

Authors:  D Salmon; F Lacassin; M Harzic; C Leport; C Perronne; F Bricaire; F Brun-Vezinet; J L Vilde
Journal:  J Med Virol       Date:  1990-11       Impact factor: 2.327

Review 10.  Serious cytomegalovirus disease in the acquired immunodeficiency syndrome (AIDS). Clinical findings, diagnosis, and treatment.

Authors:  M A Jacobson; J Mills
Journal:  Ann Intern Med       Date:  1988-04       Impact factor: 25.391
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  9 in total

1.  Comparative quantitation of cytomegalovirus (CMV) DNA in solid organ transplant recipients with CMV infection by using two high-throughput automated systems.

Authors:  R R Razonable; R A Brown; M J Espy; A Rivero; W Kremers; J Wilson; C Groettum; T F Smith; C V Paya
Journal:  J Clin Microbiol       Date:  2001-12       Impact factor: 5.948

2.  Clinical relevance of direct quantification of pp65 antigenemia using flow cytometry in solid organ and stem cell transplant recipients.

Authors:  A S Poirier-Toulemonde; N Milpied; D Cantarovich; J F Morcet; S Billaudel; B M Imbert-Marcille
Journal:  J Clin Microbiol       Date:  2000-09       Impact factor: 5.948

3.  Evaluation of the AMPLICOR cytomegalovirus test with specimens from human immunodeficiency virus-infected subjects.

Authors:  G Boivin; J Handfield; E Toma; G Murray; R Lalonde; V J Tevere; R Sun; M G Bergeron
Journal:  J Clin Microbiol       Date:  1998-09       Impact factor: 5.948

Review 4.  New strategies for prevention and therapy of cytomegalovirus infection and disease in solid-organ transplant recipients.

Authors:  I G Sia; R Patel
Journal:  Clin Microbiol Rev       Date:  2000-01       Impact factor: 26.132

5.  Quantitative analysis of cytomegalovirus (CMV) viremia using the pp65 antigenemia assay and the COBAS AMPLICOR CMV MONITOR PCR test after blood and marrow allogeneic transplantation.

Authors:  G Boivin; R Bélanger; R Delage; C Béliveau; C Demers; N Goyette; J Roy
Journal:  J Clin Microbiol       Date:  2000-12       Impact factor: 5.948

6.  Utility of major leukocyte subpopulations for monitoring secondary cytomegalovirus infections in renal-allograft recipients by PCR.

Authors:  P Schäfer; W Tenschert; L Cremaschi; K Gutensohn; R Laufs
Journal:  J Clin Microbiol       Date:  1998-04       Impact factor: 5.948

7.  Murine Cytomegalovirus Spread Depends on the Infected Myeloid Cell Type.

Authors:  Helen E Farrell; Kimberley Bruce; Clara Lawler; Philip G Stevenson
Journal:  J Virol       Date:  2019-07-17       Impact factor: 5.103

Review 8.  Quantitation of cytomegalovirus: methodologic aspects and clinical applications.

Authors:  M Boeckh; G Boivin
Journal:  Clin Microbiol Rev       Date:  1998-07       Impact factor: 26.132

9.  A prospective study comparing quantitative Cytomegalovirus (CMV) polymerase chain reaction in plasma and pp65 antigenemia assay in monitoring patients after allogeneic stem cell transplantation.

Authors:  Giuseppe Gentile; Alessandra Picardi; Angela Capobianchi; Alessandra Spagnoli; Laura Cudillo; Teresa Dentamaro; Andrea Tendas; Luca Cupelli; Marco Ciotti; Antonio Volpi; Sergio Amadori; Pietro Martino; Paolo de Fabritiis
Journal:  BMC Infect Dis       Date:  2006-11-21       Impact factor: 3.090
  9 in total

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