Literature DB >> 908433

Stereoselective activity of chiral neuroleptics.

T G White, J Schmutz.   

Abstract

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Year:  1977        PMID： 908433     DOI： 10.1007/bf01920205

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


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  12 in total

1.  Stereospecificity of interaction of neuroleptic drugs with neurotransmitters and correlation with clinical potency.

Authors:  S J Enna; J P Bennett; D R Burt; I Creese; S H Snyder
Journal:  Nature       Date:  1976-09-23       Impact factor: 49.962

2.  Neuroleptic agents of the benzocycloheptapyridoisoquinoline series. 1. Syntheses and stereochemical and structural requirements for activity of butaclamol and related compounds.

Authors:  F T Bruderlein; L G Humber
Journal:  J Med Chem       Date:  1975-02       Impact factor: 7.446

3.  Dopamine receptor binding in the corpus striatum of mammalian brain.

Authors:  D R Burt; S J Enna; I Creese; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205

4.  Effect of butaclamol and its enantiomers upon striatal homovanillic acid and adenyl cyclase of olfactory tubercle in rats.

Authors:  W Lippmann; T Pugsley; J Merker
Journal:  Life Sci       Date:  1975-01-15       Impact factor: 5.037

5.  Neuroleptic agents of the benzocycloheptapyridoisoquinoline series. A hypothesis on their mode of interaction with the central dopamine receptor.

Authors:  L G Humber; F T Bruderlein; K Voith
Journal:  Mol Pharmacol       Date:  1975-11       Impact factor: 4.436

6.  Chirality of (+)-octoclothepin, a stereospecific neuroleptic agent.

Authors:  T J Petcher; J Schmutz; H P Weber; T G White
Journal:  Experientia       Date:  1975-12-15

7.  Proceedings: Stereospecificity of neuroleptic effects in the 10-piperazino-10, 11-dihydrodibenzo (b, f) thiepin series.

Authors:  J Metysová; M Protiva
Journal:  Act Nerv Super (Praha)       Date:  1975

8.  [Stereospecifity of the neuroleptic activity and chirality of (+)-3-(2-(4-(8-fluoro-2-methyl-10, 11-dihydrodibenzo(b, f)thiepin-10-yl)-1-piperazinyl)ethyl)-2-oxazolidinone (author's transl)].

Authors:  W Aschwanden; E Kyburz; P Schönholzer
Journal:  Helv Chim Acta       Date:  1976       Impact factor: 2.164

9.  Behavioral studies on the enantiomers of butaclamol demonstrating absolute optical specificity for neuroleptic activity.

Authors:  K Voith; J R Cummings
Journal:  Can J Physiol Pharmacol       Date:  1976-08       Impact factor: 2.273

10.  8-chloro-(S)- and -(R)-10-((S)-and -(R)-3'-methylethylaminopyrrolidino)- 10,11-dihydrodibenzo(b,f)thiepins. Synthesis and pharmacological studies.

Authors:  D T Witiak; B R Vishnuvajjala; T K Gupta; M C Gerald
Journal:  J Med Chem       Date:  1976-01       Impact factor: 7.446
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