| Literature DB >> 9083836 |
C Long1, J Crifasi, D Maginn, M Graham, S Teas.
Abstract
Two venlafaxine (Effexor)-related deaths are reported with comparison of results from the analysis of specimens using capillary gas chromatography with a nitrogen-phosphorous detector (GC-NPD) and high-performance liquid chromatography (HPLC) using a UV-vis detector. Blood concentrations in Case 1 were 7.27 micrograms/mL venlafaxine and 5.03 micrograms/mL O-desmethylvenlafaxine, and Case 2 had 89.67 micrograms/mL venlafaxine with 3.44 micrograms/mL of the desmethyl metabolite. A comparison of analytical methods and specimen concentration is presented.Entities:
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Year: 1997 PMID： 9083836 DOI： 10.1093/jat/21.2.166
Source DB: PubMed Journal: J Anal Toxicol ISSN： 0146-4760 Impact factor: 3.367