Literature DB >> 9081139

Gender differences in abdominal aortic aneurysm prevalence, treatment, and outcome.

D J Katz1, J C Stanley, G B Zelenock.   

Abstract

PURPOSE: The purpose of this study was to investigate gender differences in the management of and outcome of surgery for abdominal aortic aneurysms (AAA).
METHODS: Hospital discharge data from all acute care hospitals in Michigan, as compiled in the Michigan Inpatient Data Base, were retrospectively analyzed to assess sex differences in regard to AAA prevalence, treatment, and surgical outcome from 1980 to 1990. This population database included 11,512 women and 29,846 men 50 years of age and older with diagnoses of intact or ruptured AAA.
RESULTS: Hospitalizations for intact or ruptured AAA were approximately five times more common among men compared with women. After controlling for age and year of surgery, men were 1.8 times as likely as women to have an intact AAA treated surgically and 1.4 times as likely to have a ruptured AAA treated surgically (95% confidence intervals, 1.7 to 1.9 and 1.2 to 1.7, respectively). Women who had operations for intact AAA had a 1.4 times greater risk of dying compared with men, and women who had operations for ruptured AAA had a 1.45 times greater risk of dying, after controlling for other predictors of death (95% confidence intervals, 1.14 to 1.73 and 1.10 to 1.90, respectively).
CONCLUSIONS: In a population-based statewide experience, women who had intact or ruptured AAA were less likely than men to undergo aortic reconstruction and, when they did, were less likely than men to survive to discharge.

Entities:  

Mesh:

Year:  1997        PMID: 9081139     DOI: 10.1016/s0741-5214(97)70268-4

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  27 in total

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2.  Increased estrogen receptor alpha in experimental aortic aneurysms in females compared with males.

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Review 4.  Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies-Statement From ATVB Council.

Authors:  Peggy Robinet; Dianna M Milewicz; Lisa A Cassis; Nicholas J Leeper; Hong S Lu; Jonathan D Smith
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-01-04       Impact factor: 8.311

5.  Enrollment and monitoring of women in post-approval studies for medical devices mandated by the Food and Drug Administration.

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Journal:  J Womens Health (Larchmt)       Date:  2014-01-09       Impact factor: 2.681

6.  Gender-specific differences in sex hormones and cytokines in patients undergoing major abdominal surgery.

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Review 7.  Cardiovascular Disease in Women: Clinical Perspectives.

Authors:  Mariana Garcia; Sharon L Mulvagh; C Noel Bairey Merz; Julie E Buring; JoAnn E Manson
Journal:  Circ Res       Date:  2016-04-15       Impact factor: 17.367

8.  Dietary phytoestrogens inhibit experimental aneurysm formation in male mice.

Authors:  Guanyi Lu; Gang Su; Yunge Zhao; William F Johnston; Nicholas E Sherman; Emilie F Rissman; Christine Lau; Gorav Ailawadi; Gilbert R Upchurch
Journal:  J Surg Res       Date:  2013-12-03       Impact factor: 2.192

9.  Relative importance of aneurysm diameter and body size for predicting abdominal aortic aneurysm rupture in men and women.

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Journal:  J Vasc Surg       Date:  2013-12-30       Impact factor: 4.268

10.  Decreased collagen and increased matrix metalloproteinase-13 in experimental abdominal aortic aneurysms in males compared with females.

Authors:  Brenda S Cho; Karen J Roelofs; John W Ford; Peter K Henke; Gilbert R Upchurch
Journal:  Surgery       Date:  2009-09-20       Impact factor: 3.982

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