Literature DB >> 9080608

DNA gyrase as a drug target.

A Maxwell1.   

Abstract

DNA gyrase is a remarkable enzyme, catalysing the seemingly complex reaction of DNA supercoiling. As gyrase is essential in prokaryotes, it is a good target for antibacterial agents. These agents have diverse chemical structures and interact with gyrase in a variety of ways.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9080608     DOI： 10.1016/S0966-842X(96)10085-8

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  86 in total

1.  A model for the mechanism of strand passage by DNA gyrase.

Authors:  S C Kampranis; A D Bates; A Maxwell
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

2.  Construction and characterization of mutations at codon 751 of the Escherichia coli gyrB gene that confer resistance to the antimicrobial peptide microcin B17 and alter the activity of DNA gyrase.

Authors:  F J del Castillo; I del Castillo; F Moreno
Journal:  J Bacteriol       Date:  2001-03       Impact factor: 3.490

3.  Promoter protection by a transcription factor acting as a local topological homeostat.

Authors:  Mark Rochman; Michal Aviv; Gad Glaser; Georgi Muskhelishvili
Journal:  EMBO Rep       Date:  2002-03-15       Impact factor: 8.807

4.  In vitro characterization of DNA gyrase inhibition by microcin B17 analogs with altered bisheterocyclic sites.

Authors:  D B Zamble; D A Miller; J G Heddle; A Maxwell; C T Walsh; F Hollfelder
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-26       Impact factor: 11.205

5.  A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli.

Authors:  Kevin J Cheung; Vasudeo Badarinarayana; Douglas W Selinger; Daniel Janse; George M Church
Journal:  Genome Res       Date:  2003-02       Impact factor: 9.043

6.  Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton.

Authors:  Na Pi; Caren L Freel Meyers; Michelle Pacholec; Christopher T Walsh; Julie A Leary
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-24       Impact factor: 11.205

Review 7.  Avoidance of suicide in antibiotic-producing microbes.

Authors:  Eric Cundliffe; Arnold L Demain
Journal:  J Ind Microbiol Biotechnol       Date:  2010-05-06       Impact factor: 3.346

Review 8.  Structural and functional dissection of aminocoumarin antibiotic biosynthesis: a review.

Authors:  David M Lawson; Clare E M Stevenson
Journal:  J Struct Funct Genomics       Date:  2012-05-27

9.  Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase.

Authors:  Katherine A Hurley; Thiago M A Santos; Molly R Fensterwald; Madhusudan Rajendran; Jared T Moore; Edward I Balmond; Brice J Blahnik; Katherine C Faulkner; Marie H Foss; Victoria A Heinrich; Matthew G Lammers; Lucas C Moore; Gregory D Reynolds; Galen P Shearn-Nance; Brian A Stearns; Zi W Yao; Jared T Shaw; Douglas B Weibel
Journal:  Medchemcomm       Date:  2017-02-27       Impact factor: 3.597

10.  Biological evaluation of benzothiazole ethyl urea inhibitors of bacterial type II topoisomerases.

Authors:  Neil R Stokes; Helena B Thomaides-Brears; Stephanie Barker; James M Bennett; Joanne Berry; Ian Collins; Lloyd G Czaplewski; Vicki Gamble; Paul Lancett; Alastair Logan; Christopher J Lunniss; Hilary Peasley; Stéphanie Pommier; Daniel Price; Carol Smee; David J Haydon
Journal:  Antimicrob Agents Chemother       Date:  2013-09-16       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.