| Literature DB >> 9080579 |
L Croci1, L Cozzi, A Stacchini, D De Medici, L Toti.
Abstract
Okadaic acid, the main toxin of the diarrhoetic shellfish poisoning (DSP) group, shows high cytotoxicity to Buffalo green monkey (BGM) kidney cell cultures after different times according to concentration. A rapid method of detecting the presence of okadaic acid and related compounds in contaminated mussels by means of a cytotoxicity test is presented. The method is based on direct microscopic observation of toxin-induced morphological changes in BGM cell cultures. A high correlation (r = 0.950; P < 0.001) was found between the official mouse bioassay and the cytotoxicity test conducted on naturally contaminated samples of Mytilus galloprovincialis.Entities:
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Year: 1997 PMID： 9080579 DOI： 10.1016/s0041-0101(96)00124-9
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033