Literature DB >> 908012

A simplified method for production and growth of multicellular tumor spheroids.

J M Yuhas, A P Li, A O Martinez, A J Ladman.   

Abstract

A new technique, based on the growth of tumor cells in liquid media over an agar base, has been developed for the formation and growth of multicellular tumor spheroids. All of the 11 transformed cell lines tested formed multicellular tumor spheroids, while none of the 8 normal cell types tested did so. The advantages of the present technique over older methods include its simplicity, generality, and experimental flexibility.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 908012

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  140 in total

1.  Pattern of self-organization in tumour systems: complex growth dynamics in a novel brain tumour spheroid model.

Authors:  T S Deisboeck; M E Berens; A R Kansal; S Torquato; A O Stemmer-Rachamimov; E A Chiocca
Journal:  Cell Prolif       Date:  2001-04       Impact factor: 6.831

Review 2.  Three-dimensional cultures of prostatic cells: tissue models for the development of novel anti-cancer therapies.

Authors:  K C O'Connor
Journal:  Pharm Res       Date:  1999-04       Impact factor: 4.200

3.  A simplified method for the culturing of primary adult rat and human hepatocytes as multicellular spheroids.

Authors:  A P Li; S M Colburn; D J Beck
Journal:  In Vitro Cell Dev Biol       Date:  1992 Sep-Oct

4.  The VM model of glioma: preparation of multicellular tumour spheroids (MTS) and their response to chemotherapy.

Authors:  R Bradford; J L Darling; N Sier; D G Thomas
Journal:  J Neurooncol       Date:  1990-10       Impact factor: 4.130

Review 5.  Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment.

Authors:  Hsieh-Fu Tsai; Alen Trubelja; Amy Q Shen; Gang Bao
Journal:  J R Soc Interface       Date:  2017-06       Impact factor: 4.118

6.  Three-dimensional alginate hydrogels for radiobiological and metabolic studies of cancer cells.

Authors:  Graham H Read; Natsuko Miura; Jenna L Carter; Kelsey T Kines; Kazutoshi Yamamoto; Nallathamby Devasahayam; Jason Y Cheng; Kevin A Camphausen; Murali C Krishna; Aparna H Kesarwala
Journal:  Colloids Surf B Biointerfaces       Date:  2018-06-18       Impact factor: 5.268

7.  Response of multicellular tumor spheroids to liposomes containing TNF-alpha.

Authors:  F Weber; C Kremer; M Klinkhammer; B Rasier; M Brock
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

Review 8.  Organ-on-a-chip platforms for studying drug delivery systems.

Authors:  Nupura S Bhise; João Ribas; Vijayan Manoharan; Yu Shrike Zhang; Alessandro Polini; Solange Massa; Mehmet R Dokmeci; Ali Khademhosseini
Journal:  J Control Release       Date:  2014-05-10       Impact factor: 9.776

9.  A multiphase model for three-dimensional tumor growth.

Authors:  G Sciumè; S Shelton; Wg Gray; Ct Miller; F Hussain; M Ferrari; P Decuzzi; Ba Schrefler
Journal:  New J Phys       Date:  2013-01       Impact factor: 3.729

10.  Penetration and binding of vinblastine and 5-fluorouracil in cellular spheroids.

Authors:  T Nederman; J Carlsson
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.