Literature DB >> 9079937

A Corynebacterium glutamicum gene conferring multidrug resistance in the heterologous host Escherichia coli.

W Jäger1, J Kalinowski, A Pühler.   

Abstract

A chromosomal DNA fragment from the erythromycin-sensitive bacterium Corynebacterium glutamicum ATCC 13032 was shown to mediate resistance against erythromycin, tetracycline, puromycin, and bleomycin in Escherichia coli. Multicopy cloning of the fragment did not cause a resistance phenotype in C. glutamicum. The corresponding gene encodes a hydrophobic protein with 12 potential transmembrane-spanning ex-helical segments showing similarity to drug-H+ antiporters.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9079937      PMCID： PMC178988          DOI： 10.1128/jb.179.7.2449-2451.1997

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  18 in total

1.  Expression of the Bacillus subtilis sacB gene leads to sucrose sensitivity in the gram-positive bacterium Corynebacterium glutamicum but not in Streptomyces lividans.

Authors:  W Jäger; A Schäfer; A Pühler; G Labes; W Wohlleben
Journal:  J Bacteriol       Date:  1992-08       Impact factor: 3.490

Review 2.  The biochemistry of P-glycoprotein-mediated multidrug resistance.

Authors:  J A Endicott; V Ling
Journal:  Annu Rev Biochem       Date:  1989       Impact factor: 23.643

3.  A Corynebacterium glutamicum gene encoding a two-domain protein similar to biotin carboxylases and biotin-carboxyl-carrier proteins.

Authors:  W Jäger; P G Peters-Wendisch; J Kalinowski; A Pühler
Journal:  Arch Microbiol       Date:  1996-08       Impact factor: 2.552

Review 4.  Recent developments of antibiotic research and classification of antibiotics according to chemical structure.

Authors:  J Bérdy
Journal:  Adv Appl Microbiol       Date:  1974       Impact factor: 5.086

Review 5.  Corynebacterium diphtheriae and its relatives.

Authors:  L Barksdale
Journal:  Bacteriol Rev       Date:  1970-12

Review 6.  Multidrug resistance pumps in bacteria: variations on a theme.

Authors:  K Lewis
Journal:  Trends Biochem Sci       Date:  1994-03       Impact factor: 13.807

Review 7.  Prevention of drug access to bacterial targets: permeability barriers and active efflux.

Authors:  H Nikaido
Journal:  Science       Date:  1994-04-15       Impact factor: 47.728

8.  The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers.

Authors:  J Vieira; J Messing
Journal:  Gene       Date:  1982-10       Impact factor: 3.688

9.  Sequence homology between the tetracycline-resistance determinants of Tn10 and pBR322.

Authors:  T T Nguyen; K Postle; K P Bertrand
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

10.  The pur8 gene from the pur cluster of Streptomyces alboniger encodes a highly hydrophobic polypeptide which confers resistance to puromycin.

Authors:  J A Tercero; R A Lacalle; A Jimenez
Journal:  Eur J Biochem       Date:  1993-12-15
View more
  3 in total

Review 1.  Molecular properties of bacterial multidrug transporters.

Authors:  M Putman; H W van Veen; W N Konings
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

2.  Resistance to macrolides and related antibiotics in Streptococcus pneumoniae.

Authors:  Roland Leclercq; Patrice Courvalin
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

3.  Characterization of bacterial drug antiporters homologous to mammalian neurotransmitter transporters.

Authors:  Eyal Vardy; Sonia Steiner-Mordoch; Shimon Schuldiner
Journal:  J Bacteriol       Date:  2005-11       Impact factor: 3.490
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.