| Literature DB >> 9079820 |
I Chretien1, A Marcuz, J Fellah, J Charlemagne, L Du Pasquier.
Abstract
cDNA of the T cell receptor beta (TCRB) have been isolated from the anuran amphibian Xenopus and they show strong structural homology to TCRB sequences of other vertebrates. Ten BV families, two D segments, ten J segments, and a single C region have been defined so far. Each V family consists of one to two members per haploid genome. A unique feature of the Xenopus TCRB constant region is the lack of N-linked carbohydrate glycosylation sites. The recombination signal sequences suggest that the mechanism of rearrangements are identical to those of mammals. The locus is inherited in a diploid manner despite the pseudotetraploidy of the Xenopus laevis and X. gilli used in this study.Entities:
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Year: 1997 PMID： 9079820 DOI： 10.1002/eji.1830270327
Source DB: PubMed Journal: Eur J Immunol ISSN： 0014-2980 Impact factor: 5.532