Literature DB >> 907895

The effects of etomidate on arterial pressure, pulse rate and preganglionic sympathetic activity in cats.

P Skovsted, S Sapthavichaikul.   

Abstract

We have studied the effects of etomidate on preganglionic cervical sympathetic activity, arterial pressure, and pulse rate. Normal and baroreceptor-denervated animals were studied. On the basis of findings it is concluded that etomidate exerts a minimal direct depressant action on the cardiovascular system. A profound depression of sympathetic tone was observed in spite of unaffected arterial pressure. Etomidate was also shown to possess a mild vagolytic action.

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Year:  1977        PMID: 907895     DOI: 10.1007/bf03005530

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN: 0008-2856


  5 in total

1.  The effects of althesin on arterial pressure, pulse rate preganglionic sympathetic activity and barostatic reflexes in cats.

Authors:  S Sapthavichaikul; K Wisborg; P Skovsted
Journal:  Can Anaesth Soc J       Date:  1975-09

2.  [Etomidate: cardiovascular effects of a new intravenous anesthetic agent].

Authors:  K Rifat; Z Gamulin; M Gemperle
Journal:  Can Anaesth Soc J       Date:  1976-09

3.  The effects of propanidid on arterial pressure, pulse rate, preganglionic sympathetic activity and barostatic reflexes in the cat.

Authors:  K Wisborg; S Sapthavichaikul; P Skovsted
Journal:  Can Anaesth Soc J       Date:  1977-07

4.  The effects of short-acting barbiturates on arterial pressure, preganglionic sympathetic activity and barostatic reflexes.

Authors:  P Skovsted; M L Price; H L Price
Journal:  Anesthesiology       Date:  1970-07       Impact factor: 7.892

5.  A dose-response relationship for etomidate, with some observations on cumulation.

Authors:  B Kay
Journal:  Br J Anaesth       Date:  1976-03       Impact factor: 9.166

  5 in total
  1 in total

1.  Direct measurement of vagal tone in rats does not show correlation to HRV.

Authors:  Joseph T Marmerstein; Grant A McCallum; Dominique M Durand
Journal:  Sci Rep       Date:  2021-01-13       Impact factor: 4.379

  1 in total

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