Literature DB >> 9078683

The function of costimulatory molecules and the development of IL-4-producing T cells.

W C Gause1, M J Halvorson, P Lu, R Greenwald, P Linsley, J F Urban, F D Finkelman.   

Abstract

The development of IL-4-producing effector T cells during a type 2 immune response requires signaling through B7 ligands, but probably not CD40 ligands. Here, William Gause and colleagues review the still controversial role of CD28 and CTLA-4 on T cells, and B7-1 and B7-2 on antigen-presenting cells, and provide a model to incorporate recent findings.

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Year:  1997        PMID： 9078683     DOI： 10.1016/s0167-5699(97)01005-0

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  12 in total

1.  Altering the cellular location of an antigen expressed by a DNA-based vaccine modulates the immune response.

Authors:  P J Lewis; L A Babiuk
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

2.  Experimental hypersensitivity pneumonitis: influence of Th2 bias.

Authors:  M Schuyler; K Gott; V Mapel; A Cherne; K J Nikula
Journal:  Int J Exp Pathol       Date:  1999-12       Impact factor: 1.925

3.  Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.

Authors:  G A Arreaza; M J Cameron; A Jaramillo; B M Gill; D Hardy; K B Laupland; M J Rapoport; P Zucker; S Chakrabarti; S W Chensue; H Y Qin; B Singh; T L Delovitch
Journal:  J Clin Invest       Date:  1997-11-01       Impact factor: 14.808

Review 4.  The development of CD4+ T effector cells during the type 2 immune response.

Authors:  W C Gause; M Ekkens; D Nguyen; V Mitro; Q Liu; F D Finkelman; R J Greenwald; J F Urban
Journal:  Immunol Res       Date:  1999       Impact factor: 2.829

5.  The role of B cells in the development of CD4 effector T cells during a polarized Th2 immune response.

Authors:  Qian Liu; Zhugong Liu; Cristina T Rozo; Hossein A Hamed; Farhang Alem; Joseph F Urban; William C Gause
Journal:  J Immunol       Date:  2007-09-15       Impact factor: 5.422

6.  Costimulatory molecules in Wegener's granulomatosis (WG): lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells.

Authors:  F Moosig; E Csernok; G Wang; W L Gross
Journal:  Clin Exp Immunol       Date:  1998-10       Impact factor: 4.330

7.  Antibodies to the costimulatory molecule CD86 interfere with ultraviolet radiation-induced immune suppression.

Authors:  S E Ullrich; M W Pride; A M Moodycliffe
Journal:  Immunology       Date:  1998-07       Impact factor: 7.397

8.  Role of CD80 in stimulating T lymphocyte activation.

Authors:  De-Chun Li; Xing-Guo Zhu; Yong Zhang; Jian-Xin Fu
Journal:  World J Gastroenterol       Date:  2006-02-14       Impact factor: 5.742

9.  Costimulation via lymphocyte function-associated antigen 1 in the absence of CD28 ligation promotes anergy of naive CD4+ T cells.

Authors:  J L Ragazzo; M E Ozaki; L Karlsson; P A Peterson; S R Webb
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-02       Impact factor: 11.205

10.  Expression of bcl-X(L) restores cell survival, but not proliferation off effector differentiation, in CD28-deficient T lymphocytes.

Authors:  A M Dahl; C Klein; P G Andres; C A London; M P Lodge; R C Mulligan; A K Abbas
Journal:  J Exp Med       Date:  2000-06-19       Impact factor: 14.307
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