Literature DB >> 9078682

A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells.

C E Hack1, G J Wolbink, C Schalkwijk, H Speijer, W T Hermens, H van den Bosch.   

Abstract

The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A2 and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.

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Year:  1997        PMID: 9078682     DOI: 10.1016/s0167-5699(97)01002-5

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  37 in total

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Review 3.  Regulatable gene expression systems for gene therapy.

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4.  Alkaline phosphatase and percentage body fat predict circulating C-reactive protein in premenopausal women.

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5.  Inhibition of classical complement activation attenuates liver ischaemia and reperfusion injury in a rat model.

Authors:  B H M Heijnen; I H Straatsburg; N D Padilla; G J Van Mierlo; C E Hack; T M Van Gulik
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Review 6.  C-reactive protein as a pro-inflammatory mediator in cardiovascular disease by its ability to activate complement: additional proof and hypothetical mechanisms.

Authors:  W K Lagrand; R Nijmeijer; H W M Niessen; C A Visser; W Th Hermens; C E Hack
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Review 8.  The neuroimmunology of degeneration and regeneration in the peripheral nervous system.

Authors:  A DeFrancesco-Lisowitz; J A Lindborg; J P Niemi; R E Zigmond
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9.  Matrix metalloproteinases production in malignant pleural effusions after talc pleurodesis.

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10.  Interaction of calcium-bound C-reactive protein with fibronectin is controlled by pH: in vivo implications.

Authors:  Madathilparambil V Suresh; Sanjay K Singh; Alok Agrawal
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