Literature DB >> 9077494

Prolonged duration of standing up is an early dopa-sensitive abnormality in Parkinson's disease.

B R Bloem1, K I Roon, N J Delleman, J G van Dijk, R A Roos.   

Abstract

We studied the influence of dopaminergic medication on the duration of standing up, static posture and gait in five patients with Parkinson's disease (Hoehn and Yahr stage 1.5 to 3) and four healthy controls, using an optoelectronic camera system. Duration of standing up was prolonged in patients, while static posture and gait were largely unaffected. The prolonged duration of standing up was corrected by dopaminergic medication. These results suggest that an increased duration of standing up is a relatively early and dopa-sensitive abnormality in Parkinson's disease.

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Year:  1997        PMID： 9077494     DOI： 10.1016/s0022-510x(96)00274-2

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN： 0022-510X            Impact factor:   3.181


  3 in total

1.  Effect of bilateral subthalamic nucleus stimulation on balance and finger control in Parkinson's disease.

Authors:  A M P M Vrancken; J H J Allum; M Peller; J E Visser; R A J Esselink; J D Speelman; H R Siebner; B R Bloem
Journal:  J Neurol       Date:  2005-07-21       Impact factor: 4.849

2.  Inertial measurement units furnish accurate trunk trajectory reconstruction of the sit-to-stand manoeuvre in healthy subjects.

Authors:  Daniele Giansanti; Giovanni Maccioni; Francesco Benvenuti; Velio Macellari
Journal:  Med Biol Eng Comput       Date:  2007-07-25       Impact factor: 2.602

Review 3.  Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics.

Authors:  Manfred Gerlach; Walter Maetzler; Karl Broich; Harald Hampel; Lucas Rems; Torsten Reum; Peter Riederer; Albrecht Stöffler; Johannes Streffer; Daniela Berg
Journal:  J Neural Transm (Vienna)       Date:  2011-07-14       Impact factor: 3.575
  3 in total

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