| Literature DB >> 9076604 |
M Spagnuolo1, S Kennedy, J C Foster, D A Moffett, B M Adair.
Abstract
Colostrum-deprived calves were inoculated with either a field isolate of bovine viral diarrhoea virus (BVDV) containing cytopathogenic (CP) and noncytopathogenic (NCP) biotypes or with only the NCP biotype. Paraffin wax-embedded sections of bone marrow from these calves, examined by means of an immunoperoxidase method, showed BVDV antigen in megakaryocytes and myeloid cells. Infection of such cells may play a role in the pathogenesis of thrombocytopenia, leucopenia and neutropenia, as reported in cattle infected with BVDV.Entities:
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Year: 1997 PMID： 9076604 DOI： 10.1016/s0021-9975(97)80047-3
Source DB: PubMed Journal: J Comp Pathol ISSN： 0021-9975 Impact factor: 1.311