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Literature DB >> 907328

Enhancement of antistaphylococcal activity of nafcillin and oxacillin by sisomicin and netilmicin.

Abstract

The in vitro activity of sisomicin, netilmicin, nafcillin, and oxacillin against 35 strains of Staphylococcus aureus isolated from blood cultures of patients with endocarditis or septicemia was studied. The effects of combinations of either of the two newer aminoglycosides and either of the two penicillinase-resistant penicillins on the killing of S. aureus were investigated. All S. aureus strains were susceptible to the four antibiotics. Enhancement of antistaphylococcal activity was demonstrated by the antibiotic combinations.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1977 PMID： 907328 PMCID： PMC429916 DOI： 10.1128/AAC.12.3.346

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

3 in total

1. Comparative in vitro activity of Sch 20656, netilmicin, gentamicin, and tobramycin.

Authors: C Watanakunakorn
Journal: Antimicrob Agents Chemother Date: 1976-08 Impact factor: 5.191

2. Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides.

Authors: C Watanakunakorm; C Glotzbecker
Journal: Antimicrob Agents Chemother Date: 1974-12 Impact factor: 5.191

3. Comparative activity of sisomicin, gentamicin, kanamycin, and tobramycin.

Authors: J A Waitz; E L Moss; C G Drube; M J Weinstein
Journal: Antimicrob Agents Chemother Date: 1972-12 Impact factor: 5.191

3 in total

5 in total

Enhancement of antistaphylococcal activity of nafcillin and oxacillin by sisomicin and netilmicin.

1. Comparative in vitro activity of Sch 20656, netilmicin, gentamicin, and tobramycin.

2. Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides.

3. Comparative activity of sisomicin, gentamicin, kanamycin, and tobramycin.

1. Use of synergistic antibiotics in the treatment of infections.

2. Antagonism between nafcillin or oxacillin and rifampin against Staphylococcus aureus.

Review 3. Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use.

4. Methicillin potentiates the effect of gentamicin on methicillin-resistant Staphylococcus aureus.

Review 5. Netilmicin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.