Literature DB >> 9072172

Cell cycle: will the real Cdk-activating kinase please stand up.

G F Draetta1.   

Abstract

Activation of a cyclin-dependent kinase (Cdk) requires its association with a cyclin subunit and phosphorylation on a conserved residue by the Cdk-activating kinase (CAK). The discovery in budding yeast of a novel CAK that is structurally distinct from the CAKs of other eukaryotes raises questions about the 'true' CAK.

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Year:  1997        PMID: 9072172     DOI: 10.1016/s0960-9822(06)00020-0

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  7 in total

Review 1.  Cell cycle checkpoints and their inactivation in human cancer.

Authors:  M Molinari
Journal:  Cell Prolif       Date:  2000-10       Impact factor: 6.831

2.  The rice cyclin-dependent kinase-activating kinase R2 regulates S-phase progression.

Authors:  Tanja Fabian-Marwedel; Masaaki Umeda; Margret Sauter
Journal:  Plant Cell       Date:  2002-01       Impact factor: 11.277

3.  A distinct cyclin-dependent kinase-activating kinase of Arabidopsis thaliana.

Authors:  M Umeda; R P Bhalerao; J Schell; H Uchimiya; C Koncz
Journal:  Proc Natl Acad Sci U S A       Date:  1998-04-28       Impact factor: 11.205

4.  Rux is a cyclin-dependent kinase inhibitor (CKI) specific for mitotic cyclin-Cdk complexes.

Authors:  E Foley; P H O'Farrell; F Sprenger
Journal:  Curr Biol       Date:  1999-12-02       Impact factor: 10.834

5.  T-loop phosphorylation of Arabidopsis CDKA;1 is required for its function and can be partially substituted by an aspartate residue.

Authors:  Nico Dissmeyer; Moritz K Nowack; Stefan Pusch; Hilde Stals; Dirk Inzé; Paul E Grini; Arp Schnittger
Journal:  Plant Cell       Date:  2007-03-16       Impact factor: 11.277

6.  Greatwall maintains mitosis through regulation of PP2A.

Authors:  Suzanne Vigneron; Estelle Brioudes; Andrew Burgess; Jean-Claude Labbé; Thierry Lorca; Anna Castro
Journal:  EMBO J       Date:  2009-08-13       Impact factor: 11.598

7.  Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells.

Authors:  Shi Zhong; You-Gui Li; Dong-Feng Ji; Tian-Bao Lin; Zhi-Qiang Lv
Journal:  Molecules       Date:  2016-07-19       Impact factor: 4.411

  7 in total

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