Literature DB >> 9070836

Direct interaction of the mitochondrial membrane protein carnitine palmitoyltransferase I with Bcl-2.

M B Paumen1, Y Ishida, H Han, M Muramatsu, Y Eguchi, Y Tsujimoto, T Honjo.   

Abstract

To demonstrate interaction between the mitochondrial membrane proteins CPT I and Bcl-2 the yeast two-hybrid system was used. Full-length CPT I was required for binding to Bcl-2. Direct protein interaction was confirmed in a GST binding assay and in coimmunoprecipitations using two different kinds of anti-Bcl-2 antibodies.

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Year:  1997        PMID: 9070836     DOI: 10.1006/bbrc.1997.6089

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  24 in total

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