| Literature DB >> 9070574 |
F C Aepfelbacher1, F H Messerli, E Nunez, L Michalewicz.
Abstract
The cardiovascular effects of a combination of trandolapril and verapamil were evaluated in 14 patients with mild to moderate essential hypertension. This combination therapy decreased arterial pressure mainly through a decrease in total peripheral resistance without causing an increase in heart rate or cardiac output: left ventricular mass was significantly reduced, cardiac systolic function improved, and plasma volume and renal blood flow remained unchanged.Entities:
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Year: 1997 PMID： 9070574 DOI： 10.1016/s0002-9149(96)00883-1
Source DB: PubMed Journal: Am J Cardiol ISSN： 0002-9149 Impact factor: 2.778