Literature DB >> 9069262

Lysophosphatidic acid: G-protein signalling and cellular responses.

W H Moolenaar1, O Kranenburg, F R Postma, G C Zondag.   

Abstract

Lysophosphatidic acid (LPA) is a serum-borne phospholipid that activates a specific G protein coupled receptor to evoke multiple cellular responses. Recent work has identified two cDNAs encoding putative LPA receptors, various LPA-like agonists that act on distinct receptors, and new pathways that link the receptor(s) to such diverse events as Ras signalling, cytoskeletal remodelling and membrane depolarization.

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Year:  1997        PMID： 9069262     DOI： 10.1016/s0955-0674(97)80059-2

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  87 in total

1.  Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent on sphingosine kinase activation.

Authors:  K W Young; R A Challiss; S R Nahorski; J J MacKrill
Journal:  Biochem J       Date:  1999-10-01       Impact factor: 3.857

2.  Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid.

Authors:  J A Weiner; J Chun
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

3.  CtBP1 interacts with Ikaros and modulates pituitary tumor cell survival and response to hypoxia.

Authors:  Katie Dorman; Zhongyi Shen; Caimei Yang; Shereen Ezzat; Sylvia L Asa
Journal:  Mol Endocrinol       Date:  2012-02-02

4.  Thrombin-induced growth cone collapse: involvement of phospholipase A(2) and eicosanoid generation.

Authors:  B A de La Houssaye; K Mikule; D Nikolic; K H Pfenninger
Journal:  J Neurosci       Date:  1999-12-15       Impact factor: 6.167

5.  Bcl10 plays a critical role in NF-kappaB activation induced by G protein-coupled receptors.

Authors:  Donghai Wang; Yun You; Pei-Chun Lin; Liquan Xue; Stephan W Morris; Hu Zeng; Renren Wen; Xin Lin
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-19       Impact factor: 11.205

6.  Mechanism of biological synergy between cellular Src and epidermal growth factor receptor.

Authors:  D A Tice; J S Biscardi; A L Nickles; S J Parsons
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-16       Impact factor: 11.205

7.  Different proliferative responses of Gi/o-protein-coupled receptors in human myometrial smooth muscle cells. A possible role of calcium.

Authors:  U K Nilsson; M Grenegård; G Berg; S P Svensson
Journal:  J Mol Neurosci       Date:  1998-08       Impact factor: 3.444

8.  Identification of a signaling pathway activated specifically in the somatodendritic compartment by a heparan sulfate that regulates dendrite growth.

Authors:  S Calvet; P Doherty; A Prochiantz
Journal:  J Neurosci       Date:  1998-12-01       Impact factor: 6.167

9.  Purification and characterization of a lysophosphatidic acid-specific phosphatase.

Authors:  M Hiroyama; T Takenawa
Journal:  Biochem J       Date:  1998-12-01       Impact factor: 3.857

Review 10.  Sphingosine 1-phosphate and its G protein-coupled receptors constitute a multifunctional immunoregulatory system.

Authors:  Edward J Goetzl; Wengang Wang; Christine McGiffert; Mei-Chuan Huang; Markus H Gräler
Journal:  J Cell Biochem       Date:  2004-08-15       Impact factor: 4.429
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