Literature DB >> 9069254

The state of the STATs: recent developments in the study of signal transduction to the nucleus.

C M Horvath1, J E Darnell.   

Abstract

The STATs (signal transducers and activators of transcription) are latent cytoplasmic proteins that, upon activation by cell surface bound polypeptide ligands, move to the nucleus to direct transcription. A variety of protein-protein interactions that affect the function of STATs has been recently recognized. It has become clear that the STATs are functional mosaics, or mixtures of signal transduction and transcription modules.

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Year:  1997        PMID: 9069254     DOI: 10.1016/s0955-0674(97)80067-1

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  39 in total

1.  Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis.

Authors:  T Kühbacher; P Gionchetti; J Hampe; U Helwig; P Rosenstiel; M Campieri; H J Buhr; S Schreiber
Journal:  Clin Exp Immunol       Date:  2001-03       Impact factor: 4.330

2.  Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation.

Authors:  Diane D Shao; Rahul Suresh; Varsha Vakil; Richard H Gomer; Darrell Pilling
Journal:  J Leukoc Biol       Date:  2008-03-10       Impact factor: 4.962

Review 3.  Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency.

Authors:  J J O'Shea; L D Notarangelo; J A Johnston; F Candotti
Journal:  J Clin Immunol       Date:  1997-11       Impact factor: 8.317

4.  Stat3 activation by Src induces specific gene regulation and is required for cell transformation.

Authors:  J Turkson; T Bowman; R Garcia; E Caldenhoven; R P De Groot; R Jove
Journal:  Mol Cell Biol       Date:  1998-05       Impact factor: 4.272

Review 5.  Effector and suppressor T cells in celiac disease.

Authors:  Giuseppe Mazzarella
Journal:  World J Gastroenterol       Date:  2015-06-28       Impact factor: 5.742

6.  Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription.

Authors:  Marcos Vidal; Chilakamarti V Ramana; Adriana S Dusso
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

7.  The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.

Authors:  Agata Klejman; Steven J Schreiner; Malgorzata Nieborowska-Skorska; Artur Slupianek; Matthew Wilson; Thomas E Smithgall; Tomasz Skorski
Journal:  EMBO J       Date:  2002-11-01       Impact factor: 11.598

8.  The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.

Authors:  Ravi P Sahu; Sanjay K Srivastava
Journal:  J Natl Cancer Inst       Date:  2009-01-27       Impact factor: 13.506

Review 9.  STAT3 regulation of glioblastoma pathogenesis.

Authors:  Núria de la Iglesia; Sidharth V Puram; Azad Bonni
Journal:  Curr Mol Med       Date:  2009-06       Impact factor: 2.222

10.  STAT4 contributes to adipose tissue inflammation and atherosclerosis.

Authors:  A D Dobrian; M A Hatcher; J J Brotman; E V Galkina; P Taghavie-Moghadam; H Pei; B A Haynes; J L Nadler
Journal:  J Endocrinol       Date:  2015-08-18       Impact factor: 4.286

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