| Literature DB >> 9069098 |
J J Berzas1, J Rodríguez, G Castañeda.
Abstract
A method for determining ethinylestradiol (ETE) and levonorgestrel (LEV) in mixtures by first-derivative spectrophotometry is described. The procedure does not require any separation step. Measurements are made at the zero-crossing wavelengths and the calibration graphs are linear up to 26 and 33 micrograms ml-1 of ETE and LEV, respectively. The method was applied to the determination of both compounds in five different Spanish commercial low-dose oral contraceptives. Similar results were obtained by an HPLC method.Entities:
Keywords: Contraception; Contraceptive Agents; Contraceptive Agents, Estrogen; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Developed Countries; Ethinyl Estradiol; Europe; Examinations And Diagnoses; Family Planning; Laboratory Examinations And Diagnoses; Laboratory Procedures; Levonorgestrel; Mediterranean Countries; Oral Contraceptives; Oral Contraceptives, Low-dose; Research Methodology; Research Report; Retrospective Studies; Southern Europe; Spain; Studies
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Year: 1997 PMID： 9069098 DOI： 10.1039/a604558h
Source DB: PubMed Journal: Analyst ISSN： 0003-2654 Impact factor: 4.616