L M Stern1. 1. Crippled Children's Association of South Australia, Regency Park, South Australia, Australia.
Abstract
OBJECTIVE: A study was undertaken to assess the efficacy of an oral anticholinergic drug, glycopyrrolate, in the management of drooling in children and young adults with disabilities. METHODOLOGY: Glycopyrrolate was used by 24 children and young adults for up to 28 months. Parents/carers were asked to complete a questionnaire on the effects of the drug on severity and frequency of drooling and to report any side-effects. RESULTS: Twenty-two questionnaires were returned. There was a statistically significant decrease in both severity and frequency of drooling with minimal side-effects reported. CONCLUSION: In this preliminary study, glycopyrrolate was found to be an effective and well-tolerated addition to the management of drooling in children with disabilities.
OBJECTIVE: A study was undertaken to assess the efficacy of an oral anticholinergic drug, glycopyrrolate, in the management of drooling in children and young adults with disabilities. METHODOLOGY:Glycopyrrolate was used by 24 children and young adults for up to 28 months. Parents/carers were asked to complete a questionnaire on the effects of the drug on severity and frequency of drooling and to report any side-effects. RESULTS: Twenty-two questionnaires were returned. There was a statistically significant decrease in both severity and frequency of drooling with minimal side-effects reported. CONCLUSION: In this preliminary study, glycopyrrolate was found to be an effective and well-tolerated addition to the management of drooling in children with disabilities.
Authors: Corrie E Erasmus; Karen van Hulst; Jan J Rotteveel; Michel A A P Willemsen; Peter H Jongerius Journal: Eur J Pediatr Date: 2011-09-20 Impact factor: 3.183