| Literature DB >> 9068662 |
Abstract
Some single-base changes in a 14-bp region (the downstream region) adjacent to three repeated sequences (iterons) in pSC101 ori are very deleterious for replication. We isolated a host suppressor mutation for one of these mutations and found that the suppressor suppressed all the mutations tested in the downstream region. The nucleotide sequence of the suppressor revealed that the suppressor gene was identical to dksA, which encodes a multicopy suppressor of the heat shock gene dnaK.Mesh:
Substances:
Year: 1997 PMID: 9068662 PMCID: PMC178940 DOI: 10.1128/jb.179.6.2089-2091.1997
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490