Literature DB >> 9068307

Postural drainage and gastro-oesophageal reflux in infants with cystic fibrosis.

B M Button1, R G Heine, A G Catto-Smith, P D Phelan, A Olinsky.   

Abstract

UNLABELLED: Gastro-oesophageal reflux is increased in cystic fibrosis and it is possible that postural drainage techniques may exacerbate reflux, potentially resulting in aspiration and further impairment of pulmonary function. AIM: To evaluate the effects of physiotherapy with head down tilt (standard physiotherapy, SPT) on gastroesophageal reflux and to compare this with physiotherapy without head down tilt (modified physiotherapy, MPT).
METHOD: Twenty (mean age 2.1 months) infants with cystic fibrosis underwent 30 hour oesophageal pH monitoring during which SPT and MPT were carried out for two sessions each on consecutive days.
RESULTS: The number of reflux episodes per hour, but not their duration, was significantly increased during SPT compared with MPT (SPT 2.5 (0.4) v MPT 1.6 (0.3), p = 0.007) and to background (1.1 (0.)1, p = 0.0005). Fractional reflux time was also increased during SPT (11.7 (2.6)%) compared with background (6.9 (1.3)%) p = 0.03) but not compared with MPT (10.7 (2.7)%). There was no significant difference between MPT and background for number of reflux episodes, their duration, or fractional reflux time.
CONCLUSIONS: SPT, but not MPT, was associated with a significant increase in gastro-oesophageal reflux in infants with cystic fibrosis.

Entities:  

Mesh:

Year:  1997        PMID: 9068307      PMCID: PMC1717055          DOI: 10.1136/adc.76.2.148

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


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  16 in total

Review 1.  Physiotherapy in cystic fibrosis.

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Review 2.  Structure and function of the mucus clearance system of the lung.

Authors:  Brenda M Button; Brian Button
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Journal:  Paediatr Drugs       Date:  2002       Impact factor: 3.022

Review 4.  Gastroesophageal reflux in cystic fibrosis: current understandings of mechanisms and management.

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Journal:  Curr Gastroenterol Rep       Date:  2012-06

5.  Gastro-oesophageal reflux in infants under 6 months with cystic fibrosis.

Authors:  R G Heine; B M Button; A Olinsky; P D Phelan; A G Catto-Smith
Journal:  Arch Dis Child       Date:  1998-01       Impact factor: 3.791

6.  Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands.

Authors:  Solange Abdulnour-Nakhoul; Hani N Nakhoul; Medhat I Kalliny; Alex Gyftopoulos; Edd Rabon; Rienk Doetjes; Karen Brown; Nazih L Nakhoul
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-04-06       Impact factor: 3.619

7.  Chest physiotherapy, gastro-oesophageal reflux, and arousal in infants with cystic fibrosis.

Authors:  B M Button; R G Heine; A G Catto-Smith; P D Phelan; A Olinsky
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9.  Cystic Fibrosis Foundation evidence-based guidelines for management of infants with cystic fibrosis.

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