| Literature DB >> 9068066 |
A Ponton1, J P Thirion, P Sirois.
Abstract
This paper reports on the involvement of c-MYB in the regulation of 5-lipoxygenase gene expression during differentiation of human HL-60 cells. We demonstrate that c-MYB binds the 5-lipoxygenase promoter in undifferentiated cells but not in DMSO-differentiated cells. Also, we show that overexpression of c-myb cDNA in differentiated HL-60 cells represses the 5-lipoxygenase gene expression.Entities:
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Year: 1997 PMID： 9068066 DOI： 10.1016/s0090-6980(96)00140-2
Source DB: PubMed Journal: Prostaglandins ISSN： 0090-6980