Literature DB >> 9066256

Regulation of RNA polymerases I and III by the retinoblastoma protein: a mechanism for growth control?

R J White1.   

Abstract

The retinoblastoma protein, RB, is an important tumour suppressor. Recent studies have shown that it inhibits the synthesis of both rRNA and tRNA by RNA polymerases I and III. Suppression of these important determinants of biosynthetic capacity might provide a mechanism for restraining cell growth. Loss of this control could constitute one step towards tumour progression.

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Year:  1997        PMID： 9066256     DOI： 10.1016/s0968-0004(96)10067-0

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  35 in total

1.  Repression of ribosome and tRNA synthesis in secretion-defective cells is signaled by a novel branch of the cell integrity pathway.

Authors:  Y Li; R D Moir; I K Sethy-Coraci; J R Warner; I M Willis
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

Review 2.  Survey and summary: transcription by RNA polymerases I and III.

Authors:  M R Paule; R J White
Journal:  Nucleic Acids Res       Date:  2000-03-15       Impact factor: 16.971

3.  A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70.

Authors:  M L Ferri; G Peyroche; M Siaut; O Lefebvre; C Carles; C Conesa; A Sentenac
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

4.  Overlapping functions of the pRb family in the regulation of rRNA synthesis.

Authors:  S Ciarmatori; P H Scott; J E Sutcliffe; A McLees; H M Alzuherri; J H Dannenberg; H te Riele; I Grummt; R Voit; R J White
Journal:  Mol Cell Biol       Date:  2001-09       Impact factor: 4.272

5.  RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130.

Authors:  J E Sutcliffe; C A Cairns; A McLees; S J Allison; K Tosh; R J White
Journal:  Mol Cell Biol       Date:  1999-06       Impact factor: 4.272

Review 6.  RNA polymerase III transcription: its control by tumor suppressors and its deregulation by transforming agents.

Authors:  T R Brown; P H Scott; T Stein; A G Winter; R J White
Journal:  Gene Expr       Date:  2000

7.  The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.

Authors:  H A Hirsch; L Gu; R W Henry
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

8.  Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription.

Authors:  J E Sutcliffe; T R Brown; S J Allison; P H Scott; R J White
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

9.  Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae.

Authors:  K Pluta; O Lefebvre; N C Martin; W J Smagowicz; D R Stanford; S R Ellis; A K Hopper; A Sentenac; M Boguta
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

10.  Phosphorylation by cyclin C/cyclin-dependent kinase 2 following mitogenic stimulation of murine fibroblasts inhibits transcriptional activity of LSF during G1 progression.

Authors:  Utsav H Saxena; Christina M H Powell; Jill K Fecko; Roxanne Cacioppo; Hubert S Chou; Geoffrey M Cooper; Ulla Hansen
Journal:  Mol Cell Biol       Date:  2009-02-23       Impact factor: 4.272
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